Dvorák R, Dvorák J, Vrba Z, Bouda J
Vet Med (Praha). 1980 Oct;25(10):601-14.
The effect was studied of sodium monensinate dosed 125 mg pro die and given to feeder cattle on the health condition and some clinico-biochemical parameters in view of the energy metabolism. The experiment was performed under current farming conditions in a pavilion fattening house. The experiment, which lasted 367 days, was conducted with 985 bulls of the Bohemian Spotted breed. Ten animals from the experimental and ten animals from the control pavilion were subjected to detailed clinical and clinico-biochemical examination. The feed ration was based on corn silage with an additive of dried poultry litter and concentrates. The additive was administered in the concentrate mixture, 125 mg per head/day. The health condition of the bulls was good during the whole period of study, and except several cases where neck chain wounds were observed, or small traumatic alterations on the extremities, no health disorders occurred. Some clinico-biochemical parameters of the blood were followed to study the metabolic processes and health condition. pH, pCO2, BE, SB were studied to find out the acid-base relations of the blood. As to the energy metabolism, the levels of glucose, total protein, urea, nonesterified fatty acids, triglycerides, cholesterol and total lipids were followed. Among other hematologic parameters studied there were hemoglobin, hematocrit, beta-carotene and the levels of glutamate-oxalacetate transaminase and glutamyl-transpeptidase in relation to liver metabolism. During the period of study, increased urea levels were found in the experimental animals, and on the other hand lower levels of free fatty acids and triglycerides in the blood serum. No significant changes in the other studied parameters were observed in the course of the experiment. It can be stated according to the obtained results that sodium monensinate did not influence negatively the studied clinico-biochemical parameters nor the health condition.
研究了以每日每头125毫克的剂量给育肥牛投喂莫能菌素钠对其健康状况以及一些与能量代谢相关的临床生化参数的影响。实验在当前养殖条件下的一个牛舍育肥场进行。实验持续了367天，选用了985头波希米亚斑点品种的公牛。对实验牛舍的10头动物和对照牛舍的10头动物进行了详细的临床和临床生化检查。日粮以玉米青贮料为基础，添加干家禽粪便和精饲料。添加剂添加在精饲料混合物中，每头每天125毫克。在整个研究期间，公牛的健康状况良好，除了观察到几例颈部被颈链勒伤或四肢有小创伤性改变的情况外，未发生健康问题。对血液的一些临床生化参数进行了跟踪，以研究代谢过程和健康状况。研究了pH值、pCO2、碱剩余（BE）、标准碳酸氢盐（SB）以确定血液的酸碱关系。关于能量代谢，跟踪了葡萄糖、总蛋白、尿素、非酯化脂肪酸、甘油三酯、胆固醇和总脂质的水平。在研究的其他血液学参数中，有血红蛋白、血细胞比容、β-胡萝卜素以及与肝脏代谢相关的谷氨酸草酰乙酸转氨酶和谷氨酰转肽酶的水平。在研究期间，发现实验动物的尿素水平升高，另一方面血清中游离脂肪酸和甘油三酯水平降低。在实验过程中，未观察到其他研究参数有显著变化。根据所得结果可以表明，莫能菌素钠对所研究的临床生化参数和健康状况没有负面影响。
