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[人初乳和乳汁中分泌型免疫球蛋白A的水平;48名哺乳期母亲的纵向研究]

[Levels of S-IgA in human colostrum and milk; a longitudinal study in 48 nursing mothers].

作者信息

Armenio L, Brunetti L, Diaferia P, Patano M, Mingozzi A

出版信息

Boll Soc Ital Biol Sper. 1980 May 30;56(10):1045-50.

PMID:6778487
Abstract

Human colostrum and milk collected at different times after the on-set of lactation (from 1st to 180th days) were tested for the levels of S-IgA. The technique of radial immunodiffusion with a anti-S.C. antiserum was employed. The highest percentage of S-IgA was found during the first five days post partum even if it rapidly declined during this time, thereafter remaining constant up to the 180th day of lactation. Absolute intake of S-IgA in infants during the first five days post partum was, in the same way, highest, but the amount of S-IgA intake remained high throughout the period of lactation ranging from 285 to 385 mg/die. On this basis it is suggested that breast-feeding is particularly important during the whole period of lactation and not only during its early stages.

摘要

对产后不同时间(第1天至第180天)采集的人初乳和乳汁进行了分泌型免疫球蛋白A(S-IgA)水平检测。采用了用抗分泌成分抗血清的放射免疫扩散技术。产后头五天发现S-IgA的百分比最高,即使在此期间它迅速下降,此后直至哺乳期第180天保持恒定。同样,婴儿在产后头五天的S-IgA绝对摄入量最高,但在整个哺乳期,S-IgA摄入量都很高,范围为每天285至385毫克。在此基础上,建议母乳喂养在整个哺乳期都特别重要,而不仅仅是在早期阶段。

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