Slutsky A S, Goldstein R G, Rebuck A S
Can Anaesth Soc J. 1980 Sep;27(5):445-8. doi: 10.1007/BF03007041.
The ventilatory response to carbon dioxide is known to be uninfluenced by changes in posture. To obtain similar data on the ventilatory response to hypoxia we studied seven subjects in each of two postures, lying and sitting, at a constant PCO2 midway between end-tidal and mixed venous. Minute ventilation was higher in the seated position than supine (p < 0.01) at this isocapnic level, attributable mainly to an increase in tidal volume (p < 0.05). However, there were no statistically significant differences in the ventilatory response, the tidal volume response, or the frequency response to hypoxia between the two postures.
已知对二氧化碳的通气反应不受姿势变化的影响。为了获取关于对低氧通气反应的类似数据，我们让七名受试者在两种姿势（躺卧和坐姿）下进行研究，在终末潮气与混合静脉二氧化碳分压中间值的恒定二氧化碳分压水平下。在这个等碳酸水平时，坐位时的分钟通气量高于仰卧位（p < 0.01），这主要归因于潮气量增加（p < 0.05）。然而，两种姿势之间在对低氧的通气反应、潮气量反应或频率反应方面没有统计学上的显著差异。
