Le Bihan G, Nouvet G, David P, Moynot Y, Le Loet C, Morère P
Poumon Coeur. 1980 Sep-Oct;36(5):309-12.
The authors report 43 observations of pulmonary or extra-pulmonary tuberculosis, bacteriologically proved, in which liver biopsies revealed more or less complete granulomatous lesions. The culture of 29 liver fragments on Löwenstein and Colestos medium enabled the identification of the tuberculous bacillum in only one case. In the other cases the hepatic lesion has only been related to the tuberculosis because of the clinical and bacteriological context. Therefore, besides exceptional cases where Koch bacillum is revealed in the liver parenchyma, it seems that granulomatosis can be considered a control for the delayed hypersensitivity reaction to the tuberculous antigens, and not to the tuberculous infection localized to liver.
作者报告了43例经细菌学证实的肺或肺外结核观察病例，其中肝活检显示或多或少有完整的肉芽肿病变。在罗文斯坦培养基和科莱斯托斯培养基上对29块肝组织进行培养，仅在1例中鉴定出结核杆菌。在其他病例中，肝脏病变仅因临床和细菌学背景而与结核病相关。因此，除了在肝实质中发现结核杆菌的特殊情况外，肉芽肿似乎可被视为对结核抗原迟发型超敏反应的一种表现，而非局限于肝脏的结核感染。
