Moser K M, Bokinsky G E, Savage R T, Archibald C J, Hansen P R
Arch Intern Med. 1980 Dec;140(12):1596-601.
Forty-two patients with chronic obstructive pulmonary disease participated in a comprehensive inpatient rehabilitation program. Criteria for a safe, maximum treadmill exercise regimen were established; all patients pursued this regimen for six weeks, without complications, even though 31 of 39 patients showed a decline in PaO2 with exercise. Postprogram O2 consumption, minute ventilation, heart rate, and respiratory rate were significantly reduced during exercise when compared with preprogram values. Sixteen of 29 patients improved in terms of dyspnea class; an additional 11 of these 29 improved with regard to activities of daily living. Most patients who improved physiologically also improved functionally. Patients able to tolerate higher levels of treadmill exercise initially had the greatest improvement in postcourse exercise performance. The data suggest that precourse functional and exercise classification is useful in selecting candidates who will receive the greatest functional benefits from participation in rehabilitative programs.
42例慢性阻塞性肺疾病患者参与了一项综合住院康复计划。制定了安全的最大跑步机运动方案标准；所有患者均遵循该方案进行了六周的运动，且无并发症，尽管39例患者中有31例在运动时动脉血氧分压（PaO2）下降。与运动前相比，运动后氧耗量、分钟通气量、心率和呼吸频率在运动期间显著降低。29例患者中有16例呼吸困难分级得到改善；这29例患者中另外11例在日常生活活动方面有所改善。大多数生理上得到改善的患者在功能上也有所改善。最初能够耐受更高水平跑步机运动的患者在运动后表现方面改善最大。数据表明，运动前功能和运动分类有助于选择那些将从参与康复计划中获得最大功能益处的候选人。
