Szabad J, Szidonya J
Basic Life Sci. 1980;16:95-108. doi: 10.1007/978-1-4684-7968-3_8.
The X-linked 1867+ gene seems to be a pleiotropic one. Mutation in this gene causes delay in development and abnormal bristle morphology. These phenotypes are expressed autonomously in genetic mosaics. There is no focus for the delay. The female sterility could be localized to the ovary (based on ovary transplantations). It seems that the 1867+ gene is expressed in the follicular cells at one of the last steps of oogenesis. This is suggested by the results of mosaic analysis based on mitotic recombination. Possible drawbacks of the mitotic recombination type of analyses are also discussed.
X连锁的1867+基因似乎是一个多效性基因。该基因的突变会导致发育延迟和刚毛形态异常。这些表型在遗传嵌合体中自主表达。发育延迟没有特定的集中部位。基于卵巢移植,雌性不育可能定位于卵巢。根据有丝分裂重组进行的嵌合体分析结果表明,1867+基因似乎在卵子发生的最后步骤之一的滤泡细胞中表达。本文还讨论了有丝分裂重组类型分析可能存在的缺点。