Choi C R
Arch Psychiatr Nervenkr (1970). 1978 Jun 5;225(2):97-105. doi: 10.1007/BF00343393.
EEG-driving responses to visual stimulation were studied using EEG Interval Spectrum Analysis (EISA) before and after stereotaxic thalamotomy and Nacom (L--Carbidopa and Levodopa) treatment of 67 Parkinson patients. Five types of photic-driving responses were distinguished in the EISA results: (1) all-band response, (2) Beta-dominant, (3) Alpha-Beta-dominant, (4) Alpha-Theta-dominant, (5) non-response. Twenty patients received a daily dose of 750--1000 mg of Nacom orally, and 47 patients 1000--1500 mg for a period of 3 to 4 weeks. In most cases the medication produced no change in photic-driving and EEG patterns. The photic-driving response showed no significant correlation with clinical signs and background EEG. Unilateral thalamotomy was performed in ten Parkinson patients. In two of these patients the EEG-driving response diminished in the first post-operative week for low frequency stimuli but increased after the second week.
在对67名帕金森病患者进行立体定向丘脑切开术以及使用复方卡比多巴片（左旋多巴和卡比多巴）治疗之前和之后，利用脑电图间隔频谱分析（EISA）研究了脑电图对视觉刺激的驱动反应。在EISA结果中区分出了五种类型的光驱动反应：（1）全频段反应，（2）以β波为主，（3）以α波和β波为主，（4）以α波和θ波为主，（5）无反应。20名患者口服每日剂量750 - 1000毫克的复方卡比多巴片，47名患者口服1000 - 1500毫克，为期3至4周。在大多数情况下，药物治疗并未使光驱动和脑电图模式发生改变。光驱动反应与临床体征和背景脑电图无显著相关性。对10名帕金森病患者实施了单侧丘脑切开术。其中两名患者在术后第一周低频刺激时脑电图驱动反应减弱，但在第二周后增强。
