Takaki H S, Ujiki G T, Shields T S
Am J Surg. 1977 May;133(5):548-50. doi: 10.1016/0002-9610(77)90003-4.
Seventy-eight patients underwent palliative resections for adenocarcinoma of the colon or rectum. The operative mortality was 6.4 per cent. The high morbidity rate of 43.5 per cent, mostly attributable to errors in operative technic and sepsis, could not be related to the extent of tumor spread. In fifty-nine patients long-term follow-up revealed a mean survival time of 12.4 months and a median of 9.1 months. Thirty-eight patients (64.4 per cent) survived six months, twenty patients (33.8 per cent) one year, seven patients two years, and one patient five years. Patients with only local extension of disease had the most favorable duration of survival. Hepatic or peritoneal involvement alone did not preclude long-term survival, but with the two combined the outlook was less favorable. There is a small group of patients with extensive metastatic disease who will not benefit from resection. Otherwise, adenocarcinoma of the colon or rectum with local or distant metastases should be resected when feasible.
78例患者因结肠或直肠癌接受了姑息性切除术。手术死亡率为6.4%。43.5%的高发病率主要归因于手术技术失误和脓毒症，与肿瘤扩散程度无关。在59例患者的长期随访中，平均生存时间为12.4个月，中位数为9.1个月。38例患者（64.4%）存活6个月，20例患者（33.8%）存活1年，7例患者存活2年，1例患者存活5年。仅疾病局部扩展的患者生存时间最有利。单独的肝或腹膜受累并不排除长期生存，但两者合并时预后较差。有一小部分广泛转移性疾病患者无法从切除术中获益。否则，可行时应切除有局部或远处转移的结肠或直肠癌。
