Miller D R, Allbritten F F
Arch Surg. 1976 Jun;111(6):692-6. doi: 10.1001/archsurg.1976.01360240072013.
This report is a retrospective review of the authors' experience with colonic and rectal carcinoma in 164 patients from 1954 to 1968 with a five-year follow-up. The operative approach utilized principles of early vascular isolation, wied-colon and mesenteric reseciton, and minimal tumor manipulation in curative operations; palliative procedures were aggressively employed. Of the 164 patients, 104 with lesions almost equally divided between colon and rectum had resections with curative intent. The overall five-year survival rate after curative resection was 55%, and included eight hospital deaths that were usually related to cardiopulmonary complications. Lymph node involvement appreciably decreased the survival rate from 72% without node involvement to 39% with node involvement. Patients with rectal lesions experienced more favorable results than those with colonic lesions. Palliative procedures in 46 patients enhanced comfort, but few patients survived longer than one year. Wound and anastomotic complications were infrequent.
本报告是对作者1954年至1968年间治疗的164例结肠和直肠癌患者进行的回顾性研究，随访期为五年。在根治性手术中，手术方法采用早期血管隔离、广泛结肠和肠系膜切除以及尽量减少肿瘤操作的原则；积极采用姑息性手术。164例患者中，104例病变几乎平均分布在结肠和直肠，接受了根治性切除。根治性切除后的总体五年生存率为55%，其中包括8例通常与心肺并发症相关的住院死亡病例。淋巴结受累明显降低了生存率，无淋巴结受累者的生存率为72%，有淋巴结受累者为39%。直肠病变患者的结果比结肠病变患者更理想。46例患者接受的姑息性手术提高了舒适度，但很少有患者存活超过一年。伤口和吻合口并发症很少见。
