Huggenvik J, Griswold M D
J Reprod Fertil. 1981 Mar;61(2):403-8. doi: 10.1530/jrf.0.0610403.
Cellular retinol-binding protein (CRBP) was identified in the cytosols of cultured Sertoli cells and peritubular cells from the testes of 20-day-old rats. CRBP was not detected in spermatids or spermatocytes obtained from the testes of 60-day-old rats. Cultured Sertoli cells and peritubular cells contained up to a 5-fold enrichment of CRBP/mg protein compared to whole testis homogenates. FSH- or FSH + testosterone-treated cultures of Sertoli cells showed a 60% increase in the specific activity of CRBP when compared to untreated cultures.
在20日龄大鼠睾丸的培养支持细胞和睾丸周细胞的胞质溶胶中鉴定出细胞视黄醇结合蛋白（CRBP）。在60日龄大鼠睾丸的精子细胞或精母细胞中未检测到CRBP。与整个睾丸匀浆相比，培养的支持细胞和睾丸周细胞中CRBP/毫克蛋白的含量富集高达5倍。与未处理的培养物相比，FSH或FSH+睾酮处理的支持细胞培养物中CRBP的比活性增加了60%。
