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向量心电图在小型猪中用于检测与+Gz相关的心脏病变的应用。

Use of vectorcardiography for the detection of +Gz-related cardiac pathology in miniature swine.

作者信息

Laughlin M H, Witt W M, MacKenzie W F

出版信息

Aviat Space Environ Med. 1978 Aug;49(8):972-5.

PMID:678249
Abstract

Vectorcardiograms were recorded from anesthetized, adult miniature swine 1-2 weeks before high sustained +Gz exposure and 2-6 h after exposure. Each +Gz run consisted of one 60-s exposure, respectively, to 3, 5, 7, and 9 +Gz, with 3 min rest between each +Gz plateau. The full range, from severe to minor, of +Gz-induced cardiac pathology was observed in this group of miniature swine. In spite of the large variation in the amount and degree of cardiac pathology, there were no post-exposure vectorcardiographic changes which might be diagnostic of +Gz-induced cardiac pathology. The results of this study indicate that vectorcardiography, performed after +Gz exposure, is not a reliable technique for detecting the presence of +Gz-induced cardiac pathology in miniature swine.

摘要

在成年小型猪麻醉状态下,于高持续 +Gz 暴露前 1 - 2 周及暴露后 2 - 6 小时记录心电向量图。每次 +Gz 运行分别包括一次 60 秒暴露于 3、5、7 和 9 +Gz,每个 +Gz 平台之间休息 3 分钟。在这组小型猪中观察到了从严重到轻微的 +Gz 诱导的心脏病理学全范围情况。尽管心脏病理学的数量和程度差异很大,但暴露后没有心电向量图变化可诊断为 +Gz 诱导的心脏病理学。本研究结果表明,+Gz 暴露后进行的心电向量图检查不是检测小型猪中 +Gz 诱导的心脏病理学存在的可靠技术。

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