长期使用西咪替丁后的胃蛋白酶分泌
Gastric pepsin secretion after prolonged use of cimetidine.
作者信息
Achord J L
出版信息
Am J Gastroenterol. 1980 Dec;74(6):490-2.
PMID:6782862
Abstract
Eleven patients with proven duodenal ulcer disease but no crater endoscopically were placed on a double-blind, 12-month study of cimetidine vs. placebo b.i.d. There was no evidence of either pepsin or acid rebound hypersecretion at the end of the 12-month study and no obvious differences in this small number of patients between placebo and cimetidine treatment.
摘要
11名经证实患有十二指肠溃疡病但内镜检查未发现溃疡的患者，被纳入一项为期12个月的西咪替丁与安慰剂每日两次的双盲研究。在12个月的研究结束时，没有证据表明存在胃蛋白酶或胃酸反弹性分泌过多的情况，并且在这少数患者中，安慰剂治疗和西咪替丁治疗之间没有明显差异。
相似文献
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Gastric pepsin secretion after prolonged use of cimetidine.长期使用西咪替丁后的胃蛋白酶分泌
Am J Gastroenterol. 1980 Dec;74(6):490-2.
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Acta Gastroenterol Latinoam. 1980;10(3):199-202.
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