压缩对大鼠肝脏线粒体膜的影响。一项生化与形态学研究。
Effect of compression on rat-liver mitochondrial membranes. A biochemical and morphological study.
作者信息
Wattiaux R, Wattiaux-De Coninck S, Delmelle M, Dubois F
出版信息
Acta Histochem Suppl. 1981;23:225-31.
PMID:6784170
Abstract
When rat-liver mitochondria are subjected to compression at 0 degrees C, they become permeable to sucrose and the latency of malate dehydrogenase disappears. Freeze fracture electron microscopy shows smooth areas devoid of particles in fracture faces of the membranes. The effects of pressure can be inhibited as the temperature increases. Such results are explained by supposing that compression increases the transition temperature of mitochondrial membrane lipids above 0 degrees C and causes their freezing.
摘要
当大鼠肝脏线粒体在0℃下受到压缩时，它们会对蔗糖变得通透，苹果酸脱氢酶的潜伏性消失。冷冻断裂电子显微镜显示，膜的断裂面上存在无颗粒的光滑区域。随着温度升高，压力的影响会受到抑制。这些结果可以通过假设压缩将线粒体膜脂质的转变温度提高到0℃以上并导致其冻结来解释。
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