Berman T M, Bartlett M, Westgate H D, Steiner K R, Kronenberg R S
Chest. 1981 May;79(5):536-9. doi: 10.1378/chest.79.5.536.
Ventilatory and heart rate responses to hypercapnia and hypoxia were measured in the following three groups: group I, controls (n equals 15); group II, parents of threatened sudden infant death syndrome (SIDS) infants (n equals 10); and group III, parents of SIDS infants (n equals 17). We found significantly reduced heart rate responses to carbon dioxide and hypoxia in group II (1.4 plus or minus 1.9 percent and 16.0 plus or minus 4.0 percent; mean plus or minus SEM) compared with controls (7.1 plus or minus 1.4 percent and 26 plus or minus 2.4 percent; P less than .025). Ventilatory responses to hypoxia in groups II and III were not significantly different from controls. Two group II mothers had a greatly reduce ventilatory response to carbon dioxide. Four other parents in group II had abnormally low heart rate responses to hypoxia or carbon dioxide. We concluded that parents of threatened SIDS infants had reduced heart rate responses to carbon dioxide and hypoxia and may have reduced ventilatory responses to carbon dioxide.
第一组为对照组（n = 15）；第二组为有婴儿猝死综合征（SIDS）风险婴儿的父母（n = 10）；第三组为SIDS婴儿的父母（n = 17）。我们发现，与对照组（7.1±1.4%和26±2.4%；P<0.025）相比，第二组对二氧化碳和低氧血症的心率反应显著降低（1.4±1.9%和16.0±4.0%；均值±标准误）。第二组和第三组对低氧血症的通气反应与对照组无显著差异。第二组中有两位母亲对二氧化碳的通气反应大幅降低。第二组中的另外四位父母对低氧血症或二氧化碳的心率反应异常低。我们得出结论，有SIDS风险婴儿的父母对二氧化碳和低氧血症的心率反应降低，且可能对二氧化碳的通气反应也降低。
