Frolov A A, Petukhova V M
Biofizika. 1978 Jul-Aug;23(4):668-73.
A model of the adaptive neurone was suggested to base on the effect of increasing the potassium permeability during the increasing the intracellular calcium concentration. Calcium accumulation occurs due to entrance of calcium ions into the cell in the course of the potential action development. Extent of influence of the intracellular calcium on the potassium permeability and velocity of moving the calcium off the cell was obtained from Meech's results. Frankenhauzer--Huxley equation was used for computation of membrane excitation, however, in our case the subthreshold potassium inactivation was reduced. Thus, the adaptation phenomenon was simulated in the following succession: 1) calcium accumulation in the cell, 2) increasing the potassium permeability, 3) increasing the after hyperpolarization and 4) increasing the interspike intervals.
基于细胞内钙浓度增加时钾通透性增加的效应，提出了一种适应性神经元模型。在动作电位产生过程中，由于钙离子进入细胞导致钙积累。细胞内钙对钾通透性和钙从细胞中移出速度的影响程度是从米奇的研究结果中得出的。使用弗兰克豪泽 - 赫胥黎方程计算膜兴奋，然而，在我们的情况下，阈下钾失活减少。因此，按照以下顺序模拟适应现象：1）细胞内钙积累，2）钾通透性增加，3）超极化后电位增加，4）峰间间隔增加。
