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人前列腺中的抑制素

Inhibin in the human prostate.

作者信息

Sheth A R, Panse G T, Vaze A Y, Geller J, Albert J

出版信息

Arch Androl. 1981 Jun;6(4):317-21. doi: 10.3109/01485018108987543.

DOI:10.3109/01485018108987543
PMID:6788007
Abstract

"Inhibin"-like protein, partially purified from the human prostate, was similar to that obtained from human seminal plasma under identical conditions. Concentration of inhibin in human prostate was tenfold higher as compared to human testis and was active biologically and immunologically. The presence of a high amount of inhibin in prostate seems to be unique in humans. Further inhibin concentration in benign prostatic hypertrophy tissue increased by tenfold in comparison to normal or cancerous tissue. Hence determination of serum level of inhibin may be used as a therapeutic tool to monitor prostate diseases.

摘要

从人前列腺中部分纯化得到的“抑制素”样蛋白,在相同条件下与从人精浆中获得的蛋白相似。人前列腺中抑制素的浓度比人睾丸中的高十倍,且具有生物学活性和免疫活性。前列腺中存在大量抑制素在人类中似乎是独一无二的。此外,与正常或癌组织相比,良性前列腺增生组织中抑制素的浓度增加了十倍。因此,测定血清抑制素水平可作为监测前列腺疾病的一种治疗工具。

相似文献

1
Inhibin in the human prostate.人前列腺中的抑制素
Arch Androl. 1981 Jun;6(4):317-21. doi: 10.3109/01485018108987543.
2
Isolation and characterization of inhibin from human seminal plasma.从人精浆中分离和鉴定抑制素。
Ann N Y Acad Sci. 1982;383:307-28. doi: 10.1111/j.1749-6632.1982.tb23175.x.
3
An inverse relationship exists between seminal plasma inhibin and serum follicle-stimulating hormone in man.男性精液浆抑制素与血清促卵泡激素之间存在负相关关系。
J Clin Endocrinol Metab. 1981 Apr;52(4):796-803. doi: 10.1210/jcem-52-4-796.
4
Levels of inhibin in human semen and accessory reproductive organs.
Andrologia. 1980 Jan-Feb;12(1):66-71. doi: 10.1111/j.1439-0272.1980.tb00582.x.
5
Comparative study of inhibin from human testis, prostate and seminal plasma.人睾丸、前列腺和精浆中抑制素的比较研究。
Andrologia. 1982 Sep-Oct;14(5):409-15. doi: 10.1111/j.1439-0272.1982.tb02285.x.
6
Role of the prostate in the regulation of pituitary secretion of follicle stimulating hormone.
Med Hypotheses. 1984 Oct;15(2):141-8. doi: 10.1016/0306-9877(84)90119-1.
7
Measurement of inhibin.
Arch Androl. 1980 Dec;5(4):295-303. doi: 10.3109/01485018008986999.
8
Development of a radioimmunoassay for human seminal plasma inhibin.人精浆抑制素放射免疫测定法的研制
J Reprod Fertil Suppl. 1979(26):135-46.
9
Isolation & characterization of inhibin from human seminal plasma.从人精浆中分离和鉴定抑制素
Indian J Exp Biol. 1981 Apr;19(4):307-13.
10
Isolation and characterization of a bovine seminal plasma protein inhibiting pituitary FSH secretion.一种抑制垂体促卵泡素分泌的牛精浆蛋白的分离与鉴定
Mol Cell Endocrinol. 1981 May;22(2):231-50. doi: 10.1016/0303-7207(81)90094-0.

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Prostate gland: structure, functions and regulation.前列腺:结构、功能与调节
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3
Studies on immunocytochemical localization of inhibin-like material in human prostatic tissue: comparison of its distribution in normal, benign and malignant prostates.人前列腺组织中抑制素样物质的免疫细胞化学定位研究:其在正常、良性及恶性前列腺组织中分布的比较
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