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前列腺:结构、功能与调节

Prostate gland: structure, functions and regulation.

作者信息

Kumar V L, Majumder P K

机构信息

Department of Pharmacology, All India Institute of Medical Sciences, Ansarinagar, New Delhi.

出版信息

Int Urol Nephrol. 1995;27(3):231-43. doi: 10.1007/BF02564756.

DOI:10.1007/BF02564756
PMID:7591584
Abstract

The prostate gland plays an important role in male reproduction. It secretes enzymes, lipids, amines and metal ions essential for the normal function of spermatozoa. Development, differentiation and maintenance of the prostate gland depend on steroid and peptide hormones. Beside hormones growth factors also regulate the prostate gland. This review will focus on the structure, functions and mode of regulation of the prostate gland.

摘要

前列腺在男性生殖中起着重要作用。它分泌对精子正常功能至关重要的酶、脂质、胺类和金属离子。前列腺的发育、分化和维持依赖于类固醇激素和肽类激素。除了激素,生长因子也对前列腺起到调节作用。本综述将聚焦于前列腺的结构、功能及调节方式。

相似文献

1
Prostate gland: structure, functions and regulation.前列腺:结构、功能与调节
Int Urol Nephrol. 1995;27(3):231-43. doi: 10.1007/BF02564756.
2
Polypeptide hormones and the prostate.多肽激素与前列腺
Prog Clin Biol Res. 1981;75B:63-88.
3
The endocrinology and developmental biology of the prostate.前列腺的内分泌学与发育生物学
Endocr Rev. 1987 Aug;8(3):338-62. doi: 10.1210/edrv-8-3-338.
4
The Endocrine Society Centennial: Hormones and Apoptosis in the Prostate Gland… Live and Let Die.内分泌学会百年庆典:前列腺中的激素与细胞凋亡……生存与死亡。
Endocrinology. 2016 Jun;157(6):2197-200. doi: 10.1210/en.2016-1192.
5
Expression and regulation of metallothionein mRNA levels in the prostates of noble rats: lack of expression in the ventral prostate and regulation by sex hormones in the dorsolateral prostate.贵金属大鼠前列腺中金属硫蛋白mRNA水平的表达与调控:腹侧前列腺中无表达及背外侧前列腺中受性激素调控
Prostate. 1996 Aug;29(2):91-100. doi: 10.1002/(SICI)1097-0045(199608)29:2<91::AID-PROS4>3.0.CO;2-K.
6
Hormonal oscillations during the estrous cycle influence the morphophysiology of the gerbil (Meriones unguiculatus) female prostate (skene paraurethral glands).发情周期中的激素振荡会影响沙鼠(长爪沙鼠)雌性前列腺(斯基恩尿道旁腺)的形态生理学。
Biol Reprod. 2008 Dec;79(6):1084-91. doi: 10.1095/biolreprod.108.070540. Epub 2008 Aug 6.
7
Morphologic and regulatory aspects of prostatic function.前列腺功能的形态学和调节方面。
Anat Embryol (Berl). 1989;179(6):519-31. doi: 10.1007/BF00315695.
8
[Anatomy and physiology of the prostate gland].[前列腺的解剖学与生理学]
Soins Chir. 1988 Nov(93):4-8.
9
In vivo MR elastography of the prostate gland using a transurethral actuator.使用经尿道驱动器对前列腺进行体内磁共振弹性成像
Magn Reson Med. 2009 Sep;62(3):665-71. doi: 10.1002/mrm.22038.
10
Advancing perspectives on prostate cancer: multihormonal influences in pathogenesis.前列腺癌的前沿观点:发病机制中的多激素影响
Mol Urol. 2001 Winter;5(4):181-8. doi: 10.1089/10915360152745876.

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Epigenetic insights into prostate cancer: exploring histone modifications and their therapeutic implications.前列腺癌的表观遗传学见解:探索组蛋白修饰及其治疗意义。
Front Oncol. 2025 Apr 28;15:1570193. doi: 10.3389/fonc.2025.1570193. eCollection 2025.
2
Reduction of Prostate Cancer Risk: Role of Frequent Ejaculation-Associated Mechanisms.降低前列腺癌风险:频繁射精相关机制的作用
Cancers (Basel). 2025 Feb 28;17(5):843. doi: 10.3390/cancers17050843.
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From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections.

本文引用的文献

1
Correlative electron-microscope and biochemical studies on the effect of estradiol on the rat ventral prostate.关于雌二醇对大鼠腹侧前列腺作用的相关电子显微镜及生化研究。
J Ultrastruct Res. 1960 Nov;4:166-81. doi: 10.1016/s0022-5320(60)90051-4.
2
The effects of castration and androgen replacement on the nucleic acid composition, metabolism, and enzymatic capacities of the rat ventral prostate.去势及雄激素替代对大鼠前列腺腹叶核酸组成、代谢及酶活性的影响。
Endocrinology. 1958 Sep;63(3):271-9. doi: 10.1210/endo-63-3-271.
3
Ontogeny of the cytoplasmic androgen receptor in the rat ventral prostate gland.
从垂体细胞到前列腺:健康与疾病状态下的直接和间接内分泌联系
Rev Endocr Metab Disord. 2025 Apr;26(2):187-203. doi: 10.1007/s11154-025-09948-7. Epub 2025 Feb 6.
4
The Role of Chlorella vulgaris in Attenuating Infertility Induced by Cadmium Chloride via Suppressing Oxidative Stress and Modulating Spermatogenesis and Steroidogenesis in Male Rats.小球藻在通过抑制氧化应激和调节雄性大鼠精子发生和类固醇生成从而减轻氯化镉诱导的不育症中的作用。
Biol Trace Elem Res. 2024 Sep;202(9):4007-4020. doi: 10.1007/s12011-023-03971-y. Epub 2023 Dec 20.
5
Quercetin Abates Aluminum Trioxide Nanoparticles and Lead Acetate Induced Altered Sperm Quality, Testicular Oxidative Damage, and Sexual Hormones Disruption in Male Rats.槲皮素减轻三氧化二铝纳米颗粒和醋酸铅诱导的雄性大鼠精子质量改变、睾丸氧化损伤及性激素紊乱。
Antioxidants (Basel). 2022 Oct 28;11(11):2133. doi: 10.3390/antiox11112133.
6
Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (<em>Spermophilus dauricus</em>).野生黄鼠 (<em>Spermophilus dauricus</em>) 前列腺中 VEGF 及其受体 VEGFR1 和 VEGFR2 的季节表达。
Eur J Histochem. 2021 Mar 24;65(2):3219. doi: 10.4081/ejh.2021.3219.
7
Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue.人前列腺癌组织周边区和移行区的类固醇生成。
Int J Mol Sci. 2021 Jan 6;22(2):487. doi: 10.3390/ijms22020487.
8
Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders.50岁以上男性的锌缺乏及其对前列腺疾病的影响。
Front Oncol. 2020 Aug 6;10:1293. doi: 10.3389/fonc.2020.01293. eCollection 2020.
9
Jumping on the Bandwagon: A Review on the Versatile Applications of Gold Nanostructures in Prostate Cancer.随大流:金纳米结构在前列腺癌中的多种应用综述。
Int J Mol Sci. 2019 Feb 23;20(4):970. doi: 10.3390/ijms20040970.
10
The effect of anthocyanin on the prostate in an andropause animal model: rapid prostatic cell death by apoptosis is partially prevented by anthocyanin supplementation.花色苷对去势动物模型前列腺的作用:花色苷补充可部分预防前列腺细胞快速凋亡。
World J Mens Health. 2013 Dec;31(3):239-46. doi: 10.5534/wjmh.2013.31.3.239. Epub 2013 Dec 24.
大鼠腹侧前列腺中细胞质雄激素受体的个体发生。
Biol Reprod. 1980 Oct;23(3):518-21. doi: 10.1095/biolreprod23.3.518.
4
Specific high-affinity oestradiol binding in rat ventral prostate.大鼠腹侧前列腺中特异性高亲和力雌二醇结合
J Endocrinol. 1980 Nov;87(2):285-92. doi: 10.1677/joe.0.0870285.
5
Functionality of estrogen receptor and tamoxifen treatment of R3327 Dunning rat prostate adenocarcinoma.雌激素受体的功能及他莫昔芬对R3327邓宁大鼠前列腺腺癌的治疗作用
Cancer Res. 1980 Jul;40(7):2188-93.
6
Androgen regulation of androgen receptor content and distribution in the ventral and dorsolateral prostates of aging AXC rats.雄激素对衰老AXC大鼠腹侧前列腺和背外侧前列腺中雄激素受体含量及分布的调节作用。
Steroids. 1980 Feb;35(2):157-77. doi: 10.1016/0039-128x(80)90100-2.
7
Estrogen regulation of rat prostate androgen receptor.雌激素对大鼠前列腺雄激素受体的调节作用。
J Steroid Biochem. 1981 Dec;15:403-8. doi: 10.1016/0022-4731(81)90305-8.
8
Aging in the AXC rat: differential effects of chronic testosterone treatment on restoration of diminished prostate L-ornithine decarboxylase and S-adenosyl-L-methionine decarboxylase activities.AXC大鼠的衰老:慢性睾酮治疗对恢复前列腺中降低的L-鸟氨酸脱羧酶和S-腺苷-L-甲硫氨酸脱羧酶活性的不同影响。
Endocrinology. 1981 Oct;109(4):1184-91. doi: 10.1210/endo-109-4-1184.
9
The zonal anatomy of the prostate.前列腺的分区解剖
Prostate. 1981;2(1):35-49. doi: 10.1002/pros.2990020105.
10
Effect of endocrine manipulations on the levels of cytosolic and nuclear receptors for androgens in dog prostate.内分泌调控对犬前列腺雄激素胞质受体和核受体水平的影响。
Invest Urol. 1981 May;18(8):418-21.