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多种抗癌药物增强迟发型超敏反应。一种常见的生物学现象。

Enhancement of delayed hypersensitivity reaction with varieties of anti-cancer drugs. A common biological phenomenon.

作者信息

Goto M, Mitsuoka A, Sugiyama M, Kitano M

出版信息

J Exp Med. 1981 Jul 1;154(1):204-9. doi: 10.1084/jem.154.1.204.

Abstract

Delayed hypersensitivity reaction in mice was commonly enhanced with various anti-cancer agents administered as single or intermittent high doses but not consecutive divided doses. The effect of anti-cancer agents on the delayed hypersensitivity reaction was thought to be due to elimination of suppressor T cell activity.

摘要

小鼠的迟发型超敏反应通常会因各种抗癌药物以单次或间歇性高剂量给药而增强,但连续分次给药则不会。抗癌药物对迟发型超敏反应的作用被认为是由于抑制性T细胞活性的消除。

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