Phase I study of high doses of methotrexate with citrovorum factor in patients with lung cancer.

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作者信息

Djerassi I, Rominger C J, Kim J S, Turchi J, Suvansri U, Hughes D

出版信息

Cancer. 1972 Jul;30(1):22-30. doi: 10.1002/1097-0142(197207)30:1<22::aid-cncr2820300105>3.0.co;2-b.

DOI:10.1002/1097-0142(197207)30:1<22::aid-cncr2820300105>3.0.co;2-b

PMID:4537740

Abstract

摘要

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Phase I study of high doses of methotrexate with citrovorum factor in patients with lung cancer.

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Effect of methotrexate concentration and exposure time on mammalian cell survival in vitro.甲氨蝶呤浓度和暴露时间对体外培养的哺乳动物细胞存活的影响。

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The inability of oral leucovorin to elevate CSF 5-methyl-tetrahydrofolate following high dose intravenous methotrexate therapy.

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Combination chemotherapy (high-dose methotrexate with citrovorum factor rescue, mechlorethamine, and procarbazine) in non-small cell lung cancer.

Cancer Chemother Pharmacol. 1983;11(2):106-7. doi: 10.1007/BF00254256.

A microbiological assay for the measurement of methotrexate in biological fluids.一种用于测量生物体液中甲氨蝶呤的微生物学测定法。

J Clin Pathol. 1983 Oct;36(10):1116-9. doi: 10.1136/jcp.36.10.1116.

Methotrexate and methotrexate polyglutamates in human sarcoma metastases after high-dose methotrexate therapy.

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