通过红细胞阴离子转运系统进行的氨基酸转运。
Amino acid transport via the red cell anion transport system.
作者信息
Young J D, Jones S E, Ellory J C
出版信息
Biochim Biophys Acta. 1981 Jul 6;645(1):157-60. doi: 10.1016/0005-2736(81)90524-1.
PMID:6789878
Abstract
Evidence is presented that the red cell anion-exchange transporter (Band 3) can selectively transport small neutral amino acids, including glycine, serine and cysteine, but not alanine, proline, valine and threonine. This transport is inhibited by micromolar concentrations of SITS (4-acetamido-4'-isothiocyanostilbene-2,2'-disulphonate), and increased by raising the pH from 6.5 to 8.5.
摘要
有证据表明，红细胞阴离子交换转运体（带3蛋白）能够选择性转运包括甘氨酸、丝氨酸和半胱氨酸在内的中性小氨基酸，但不能转运丙氨酸、脯氨酸、缬氨酸和苏氨酸。这种转运受到微摩尔浓度的SITS（4-乙酰氨基-4'-异硫氰基芪-2,2'-二磺酸盐）的抑制，并且随着pH值从6.5升高到8.5而增强。
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