正常及谷胱甘肽缺乏的绵羊红细胞中的氨基酸转运
Amino acid transport in normal and glutathione-deficient sheep erythrocytes.
作者信息
Young J D, Ellory J C, Tucker E M
出版信息
Biochem J. 1976 Jan 15;154(1):43-8. doi: 10.1042/bj1540043.
Abstract
- Uptake rates for 23 amino acids were measured for both normal (high-GSH) and GSH-deficient (low-GSH) erythrocytes from Finnish Landrace sheep. 2. Compared with high-GSH cells, low-GSH cells had a markedly diminished permeability to D-alanine, L-alanine, alpha-amino-n-butyrate, valine, cysteine, serine, threonine, asparagine, lysine and ornithine. Smaller differences were observed for glycine and proline, whereas uptake of the other amino acids was not significantly different in the two cell types.
摘要
- 对芬兰长白绵羊的正常（高谷胱甘肽）和谷胱甘肽缺乏（低谷胱甘肽）红细胞的23种氨基酸摄取率进行了测量。2. 与高谷胱甘肽细胞相比，低谷胱甘肽细胞对D-丙氨酸、L-丙氨酸、α-氨基-n-丁酸盐、缬氨酸、半胱氨酸、丝氨酸、苏氨酸、天冬酰胺、赖氨酸和鸟氨酸的通透性明显降低。甘氨酸和脯氨酸的差异较小，而两种细胞类型中其他氨基酸的摄取没有显著差异。
相似文献
1
Amino acid transport in normal and glutathione-deficient sheep erythrocytes.
Biochem J. 1976 Jan 15;154(1):43-8. doi: 10.1042/bj1540043.
2
Substrate specificity of amino acid transport in sheep erythrocytes.
Biochem J. 1977 Jan 15;162(1):33-8. doi: 10.1042/bj1620033.
3
Characterization of normal, glutathione-deficient and arginase-deficient sheep erythrocytes by 1H-NMR spectroscopy.
Biochim Biophys Acta. 1985 Aug 30;846(2):200-7. doi: 10.1016/0167-4889(85)90066-7.
4
GSH biosynthesis in glutathione deficient erythrocytes from Finnish landrace and Tasmanian merino sheep.
Biochim Biophys Acta. 1975 Sep 8;404(1):132-41. doi: 10.1016/0304-4165(75)90154-3.
5
Genetic control of amino acid transport in sheep erythrocytes.
Biochem Genet. 1982 Aug;20(7-8):723-31. doi: 10.1007/BF00483969.
6
Amino acid transport defect in glutathione-deficient sheep erythrocytes.
Nature. 1975 Mar 13;254(5496):156-7. doi: 10.1038/254156a0.
7
Amino acid transport via the red cell anion transport system.
Biochim Biophys Acta. 1981 Jul 6;645(1):157-60. doi: 10.1016/0005-2736(81)90524-1.
8
Biochemical changes during reticulocyte maturation in culture. A comparison of genetically different sheep erythrocytes.
Biochem J. 1980 Oct 15;192(1):33-9. doi: 10.1042/bj1920033.
9
Amino acid transport properties of erythrocytes from normal newborn lambs and lambs with an inherited defect in amino acid transport.
Biochim Biophys Acta. 1978 Aug 17;511(3):513-6. doi: 10.1016/0005-2736(78)90286-9.
10
Effect of substrate structure on coupling ratio for Na + -dependent transport of amino acids.
Biochim Biophys Acta. 1971 Jul 6;241(1):9-19. doi: 10.1016/0005-2736(71)90298-7.
引用本文的文献
1
Glycine transport in human erythrocytes.
J Physiol. 1981 Nov;320:403-22. doi: 10.1113/jphysiol.1981.sp013958.
2
Biochemical changes during reticulocyte maturation in culture. A comparison of genetically different sheep erythrocytes.
Biochem J. 1980 Oct 15;192(1):33-9. doi: 10.1042/bj1920033.
3
Genetic control of amino acid transport in sheep erythrocytes.
Biochem Genet. 1982 Aug;20(7-8):723-31. doi: 10.1007/BF00483969.
4
Red-cell amino acid transport. Evidence for the presence of system ASC in mature human red blood cells.
Biochem J. 1983 Nov 15;216(2):349-57. doi: 10.1042/bj2160349.
5
Nucleoside translocation in sheep reticulocytes and fetal erythrocytes: a proposed model for the nucleoside transporter.
J Physiol. 1982 Mar;324:47-66. doi: 10.1113/jphysiol.1982.sp014100.
6
Abnormal gamma-glutamylcysteine synthetase activities in sheep red blood cells.
Biochem Genet. 1983 Oct;21(9-10):907-22. doi: 10.1007/BF00483949.
7
Characterization of a novel Na+-independent amino acid transporter in horse erythrocytes.
Biochem J. 1985 Apr 1;227(1):13-20. doi: 10.1042/bj2270013.
8
Heterogeneity of amino acid transport in horse erythrocytes: a detailed kinetic analysis of inherited transport variation.
J Physiol. 1987 Aug;389:385-409. doi: 10.1113/jphysiol.1987.sp016662.
9
Role of membrane transport in metabolism and function of glutathione in mammals.
J Membr Biol. 1986;89(1):1-8. doi: 10.1007/BF01870891.
10
Na- and Cl-dependent glycine transport in human red blood cells and ghosts. A study of the binding of substrates to the outward-facing carrier.
J Gen Physiol. 1989 Feb;93(2):321-42. doi: 10.1085/jgp.93.2.321.
本文引用的文献
1
AMINO ACID TRANSPORT IN BLOOD CELLS. II. PATTERNS OF TRANSPORT OF SOME AMINO ACIDS IN MAMMALIAN RETICULOCYTES AND MATURE RED BLOOD CELLS.
J Lab Clin Med. 1965 Aug;66:177-86.
2
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
J Biol Chem. 1964 Mar;239:872-8.
3
Contrasts in neutral amino acid transport by rabbit erythrocytes and reticulocytes.
J Biol Chem. 1965 Sep;240(9):3594-600.
4
Differences in schedules of regression of transport systems during reticulocyte maturation.
J Biol Chem. 1969 Mar 25;244(6):1505-9.
5
An inherited glutathione deficiency and a concomitant reduction in potassium concentration in sheep red cells.
Experientia. 1970;26(2):203-4. doi: 10.1007/BF01895584.
6
The identification of ornithine and lysine at high concentrations in the red cells of sheep with an inherited deficiency of glutathione.
Biochim Biophys Acta. 1972 Oct 25;279(3):481-3. doi: 10.1016/0304-4165(72)90169-9.
7
The transport of L-leucine in human erythrocytes: a new kinetic analysis.
J Physiol. 1972 Mar;221(2):311-29. doi: 10.1113/jphysiol.1972.sp009753.
8
Transport of dibasic amino acids by human erythrocytes.
Metabolism. 1972 May;21(5):413-31. doi: 10.1016/0026-0495(72)90054-6.
9
Some special kinetic problems of transport.
Adv Enzymol Relat Areas Mol Biol. 1969;32:1-20. doi: 10.1002/9780470122778.ch1.
10
Amino acid transport defect in glutathione-deficient sheep erythrocytes.
Nature. 1975 Mar 13;254(5496):156-7. doi: 10.1038/254156a0.
Zotero 插件