正常及谷胱甘肽缺乏的绵羊红细胞中的氨基酸转运
Amino acid transport in normal and glutathione-deficient sheep erythrocytes.
作者信息
Young J D, Ellory J C, Tucker E M
出版信息
Biochem J. 1976 Jan 15;154(1):43-8. doi: 10.1042/bj1540043.
Abstract
- Uptake rates for 23 amino acids were measured for both normal (high-GSH) and GSH-deficient (low-GSH) erythrocytes from Finnish Landrace sheep. 2. Compared with high-GSH cells, low-GSH cells had a markedly diminished permeability to D-alanine, L-alanine, alpha-amino-n-butyrate, valine, cysteine, serine, threonine, asparagine, lysine and ornithine. Smaller differences were observed for glycine and proline, whereas uptake of the other amino acids was not significantly different in the two cell types.
摘要
- 对芬兰长白绵羊的正常（高谷胱甘肽）和谷胱甘肽缺乏（低谷胱甘肽）红细胞的23种氨基酸摄取率进行了测量。2. 与高谷胱甘肽细胞相比，低谷胱甘肽细胞对D-丙氨酸、L-丙氨酸、α-氨基-n-丁酸盐、缬氨酸、半胱氨酸、丝氨酸、苏氨酸、天冬酰胺、赖氨酸和鸟氨酸的通透性明显降低。甘氨酸和脯氨酸的差异较小，而两种细胞类型中其他氨基酸的摄取没有显著差异。
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