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果蝇多线染色体中核仁的定位

Localization of nucleoli in Drosophila melanogaster polytene chromosomes.

作者信息

Ananiev E V, Barsky V E, Ilyin Y V, Churikov N A

出版信息

Chromosoma. 1981;81(4):619-28. doi: 10.1007/BF00285853.

DOI:10.1007/BF00285853
PMID:6790245
Abstract

The majority of D. melanogaster salivary gland nuclei contains many nucleoli which vary in size and number. All nucleoli hybridize in situ with a cloned Drosophila DNA fragment containing 26S ribosomal gene. Autoradiographic analysis of preparations after pulse H3-uridine or H3-thymidine labelling of the salivary gland indicates an intensive transcription and replication of DNA within nucleoli. The nucleoli are bound to different sites of polytene chromosomes by chromatin fibers similar to strands of ectopic pairing and they are most often bound to regions which may be defined as intercalary heterochromatin.

摘要

大多数黑腹果蝇唾液腺细胞核含有许多核仁，其大小和数量各不相同。所有核仁都能与一个含有26S核糖体基因的克隆果蝇DNA片段进行原位杂交。对唾液腺进行脉冲H3-尿苷或H3-胸苷标记后制备物的放射自显影分析表明，核仁内DNA有强烈的转录和复制。核仁通过类似于异位配对链的染色质纤维与多线染色体的不同位点相连，并且它们最常与可定义为居间异染色质的区域相连。

相似文献

1
Localization of nucleoli in Drosophila melanogaster polytene chromosomes.果蝇多线染色体中核仁的定位
Chromosoma. 1981;81(4):619-28. doi: 10.1007/BF00285853.
2
Transcription of intercalary heterochromatin regions in Drosophila melanogaster cell culture.黑腹果蝇细胞培养中居间异染色质区域的转录
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[Transcription of portions of chromosomes corresponding to regions of intercalary heterochromatin in Drosophila melanogaster cell cultures].[果蝇细胞培养中与居间异染色质区域相对应的部分染色体的转录]
Genetika. 1980;16(10):1729-40.
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Reiterated genes with varying location in intercalary heterochromatin regions of Drosophila melanogaster polytene chromosomes.在黑腹果蝇多线染色体的居间异染色质区域中具有不同位置的重复基因。
Chromosoma. 1978 Dec 21;70(1):1-17. doi: 10.1007/BF00292211.
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The faint band/interband region 28C2 to 28C4-5(-) of the Drosophila melanogaster salivary gland polytene chromosomes is rich in transcripts.黑腹果蝇唾液腺多线染色体上28C2至28C4 - 5（ - ）的微弱带/间带区域富含转录本。
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Three euchromatic DNA sequences under-replicated in polytene chromosomes of Drosophila are localized in constrictions and ectopic fibers.在果蝇多线染色体中复制不足的三个常染色质DNA序列位于缢痕和异位纤维中。
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Overexpression of the SuUR gene induces reversible modifications at pericentric, telomeric and intercalary heterochromatin of Drosophila melanogaster polytene chromosomes.SuUR基因的过表达会在黑腹果蝇多线染色体的着丝粒周围、端粒和居间异染色质处诱导可逆修饰。
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Replication in Drosophila chromosomes. VII. Influence of prolonged larval life on patterns of replication in polytene chromosomes of Drosophila melanogaster.果蝇染色体的复制。VII. 幼虫期延长对黑腹果蝇多线染色体复制模式的影响。
Chromosoma. 1982;85(2):221-36. doi: 10.1007/BF00294967.

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本文引用的文献

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Repeated sequences in the DNA of Drosophila and their localization in giant chromosomes.果蝇DNA中的重复序列及其在巨大染色体中的定位。
Chromosoma. 1970 Dec 2;32(1):31-63. doi: 10.1007/BF00334010.
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In situ demonstration of DNA hybridizing with chromosomal and nuclear sap RNA in Chironomus tentans.摇蚊中DNA与染色体及核液RNA杂交的原位显示
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Cytological localization of DNA complementary to ribosomal RNA in polytene chromosomes of Diptera.双翅目多线染色体中与核糖体RNA互补的DNA的细胞学定位。
Induction of the Erythroid Differentiation of K562 Cells Is Coupled with Changes in the Inter-Chromosomal Contacts of rDNA Clusters.
K562 细胞的红细胞分化诱导伴随着 rDNA 簇的染色体间接触变化。
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The Role of rDNA Clusters in Global Epigenetic Gene Regulation.核糖体DNA簇在全基因组表观遗传基因调控中的作用
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Dynamics of Whole-Genome Contacts of Nucleoli in Cells Suggests a Role for rDNA Genes in Global Epigenetic Regulation.核仁全基因组接触的动力学表明 rDNA 基因在全局表观遗传调控中的作用。
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Interchromosomal Contacts of rDNA Clusters with DUX Genes in Human Chromosome 4 Are Very Sensitive to Heat Shock Treatment.rDNA 簇与人类染色体 4 上的 DUX 基因的染色体间接触对热休克处理非常敏感。
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rDNA Clusters Make Contact with Genes that Are Involved in Differentiation and Cancer and Change Contacts after Heat Shock Treatment.rDNA 簇与参与分化和癌症的基因接触，并在热休克处理后改变接触。
Cells. 2019 Nov 5;8(11):1393. doi: 10.3390/cells8111393.
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Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure.连接组蛋白H1对果蝇发育、着丝粒周围异染色质的建立以及正常的多线染色体结构至关重要。
Genes Dev. 2009 Feb 15;23(4):452-65. doi: 10.1101/gad.1749309. Epub 2009 Feb 4.
9
Changes in chromatin structure correlate with transcriptional activity of nucleolar rDNA in polytene chromosomes.染色质结构的变化与多线染色体中核仁rDNA的转录活性相关。
Chromosoma. 2009 Jun;118(3):303-22. doi: 10.1007/s00412-008-0198-9. Epub 2008 Dec 9.
10
Gene and genon concept: coding versus regulation. A conceptual and information-theoretic analysis of genetic storage and expression in the light of modern molecular biology.基因与基因子概念：编码与调控。基于现代分子生物学对遗传信息存储与表达的概念及信息论分析。
Theory Biosci. 2007 Oct;126(2-3):65-113. doi: 10.1007/s12064-007-0012-x. Epub 2007 Sep 22.
Chromosoma. 1970;29(3):268-90. doi: 10.1007/BF00325943.
4
Independent control of ribosomal gene replication in polytene chromosomes of Drosophila melanogaster.黑腹果蝇多线染色体中核糖体基因复制的独立控制。
Proc Natl Acad Sci U S A. 1973 May;70(5):1359-63. doi: 10.1073/pnas.70.5.1359.
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Ectopic pairing of chromosome regions containing chemically similar DNA.含有化学性质相似的DNA的染色体区域的异位配对。
Chromosoma. 1972;39(1):53-61. doi: 10.1007/BF00320590.
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A reinvestigation of the nucleolus-organizing regions in the salivary gland nuclei of Drosophila melanogaster.对黑腹果蝇唾液腺细胞核仁组织区的重新研究。
Chromosoma. 1971;36(1):34-45. doi: 10.1007/BF00326420.
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Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.菌落杂交：一种分离含有特定基因的克隆DNA的方法。
Proc Natl Acad Sci U S A. 1975 Oct;72(10):3961-5. doi: 10.1073/pnas.72.10.3961.
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Arrangement of length heterogeneity in repeating units of amplified and chromosomal ribosomal DNA from Xenopus laevis.非洲爪蟾扩增的核糖体DNA和染色体核糖体DNA重复单元中长度异质性的排列
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Unintegrated ribosomal genes in diploid and polytene tissues of Drosophila melanogaster.黑腹果蝇二倍体和多线组织中的未整合核糖体基因。
Chromosoma. 1976 Nov 19;58(3):235-46. doi: 10.1007/BF00292089.
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Ectopic pairing and evolution of 5S ribosomal RNA genes in the chromosomes of Drosophila funebris.黑腹果蝇染色体中5S核糖体RNA基因的异位配对与进化
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