Hempel V, Heller W, Graf H
Infusionsther Klin Ernahr. 1981 Jun;8(3):124-32.
Two groups of patients with multiple injuries were treated with high-caloric parenteral nutrition over a period of 10 days. One group received amino acids (1 g/kg BW/day) and dextrose (2.0 x resting metabolic rate calories). In the other group dextrose was partially substituted by an isocaloric amount of lipids (2 g/kg BW/day). As for blood and serum glucose, pyruvate, lactate, triglycerides, cholesterol, phosphatides, free fatty acids, glycerol, acetoacetate and beta-hydroxybutyrate there were no significant differences between the two groups. Nevertheless, in the lipid group more balanced blood-sugar levels were seen with smaller amounts of insulin to be needed. This suggests a beneficial effect on the carbohydrate metabolism.
两组多发伤患者接受了为期10天的高热量肠外营养治疗。一组接受氨基酸(1克/千克体重/天)和葡萄糖(2.0×静息代谢率卡路里)。另一组中,葡萄糖被等热量的脂质(2克/千克体重/天)部分替代。至于血液和血清中的葡萄糖、丙酮酸、乳酸、甘油三酯、胆固醇、磷脂、游离脂肪酸、甘油、乙酰乙酸和β-羟基丁酸,两组之间没有显著差异。然而,脂质组的血糖水平更平衡,所需胰岛素量更少。这表明对碳水化合物代谢有有益作用。