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Development of tolerance to the pulmonary toxin, 4-ipomeanol.

作者信息

Boyd M R, Burka L T, Wilson B J, Sastry B V

出版信息

Toxicology. 1981;19(2):85-100. doi: 10.1016/0300-483x(81)90091-3.

DOI:10.1016/0300-483x(81)90091-3
PMID:6791310
Abstract
摘要

相似文献

1
Development of tolerance to the pulmonary toxin, 4-ipomeanol.对肺部毒素4-异戊二烯醇的耐受性发展
Toxicology. 1981;19(2):85-100. doi: 10.1016/0300-483x(81)90091-3.
2
In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol.关于靶器官烷基化与4-异戊烯醇化学反应性代谢物肺毒性之间关系的体内研究。
J Pharmacol Exp Ther. 1978 Dec;207(3):687-97.
3
Species and strain differences in target organ alkylation and toxicity by 4-ipomeanol. Predictive value of covalent binding in studies of target organ toxicities by reactive metabolites.
Biochem Pharmacol. 1979 Dec 1;28(23):3367-72. doi: 10.1016/0006-2952(79)90074-1.
4
Whole body plethysmography as a noninvasive assay of toxic lung injury in mice: studies with the pulmonary alkylating agent and cytotoxin, 4-ipomeanol.全身体积描记法作为小鼠中毒性肺损伤的非侵入性检测方法：使用肺部烷基化剂和细胞毒素4-异戊烯醇的研究
Toxicol Appl Pharmacol. 1982 Nov;66(2):193-200. doi: 10.1016/0041-008x(82)90284-8.
5
Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol.代谢活化在化学诱导的肺部疾病发病机制中的作用：肺毒性呋喃4-异戊烯醇的作用机制
Environ Health Perspect. 1976 Aug;16:127-38. doi: 10.1289/ehp.7616127.
6
In vitro studies on the metabolic activation of the pulmonary toxin, 4-ipomeanol, by rat lung and liver microsomes.大鼠肺和肝微粒体对肺毒素4-异戊二烯醇代谢激活的体外研究。
J Pharmacol Exp Ther. 1978 Dec;207(3):677-86.
7
Effect of carbon monoxide on the cytochrome P-450-mediated activation of 4-ipomeanol by the isolated perfused rabbit lung.一氧化碳对离体灌注兔肺中细胞色素P-450介导的4-异蒲勒醇活化作用的影响。
J Toxicol Environ Health. 1989;27(3):341-50. doi: 10.1080/15287398909531305.
8
Protective role of endogenous pulmonary glutathione and other sulfhydryl compounds against lung damage by alkylating agents. Investigations with 4-ipomeanol in the rat.内源性肺谷胱甘肽及其他巯基化合物对烷基化剂所致肺损伤的保护作用。用4-异亚丙基丙酮对大鼠进行的研究。
Biochem Pharmacol. 1982 Apr 15;31(8):1579-83. doi: 10.1016/0006-2952(82)90383-5.
9
Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
Biochem Biophys Res Commun. 1980 Apr 29;93(4):1167-72. doi: 10.1016/0006-291x(80)90612-9.
10
The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol.兔肺细胞色素P-450同工酶的催化活性与呋喃衍生物4-异戊烯醇的肺特异性毒性之间的关系。
Mol Pharmacol. 1982 Nov;22(3):738-44.

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Use of nuclear magnetic resonance-based metabolomics to characterize the biochemical effects of naphthalene on various organs of tolerant mice.利用基于核磁共振的代谢组学来表征萘对耐受小鼠各器官的生化影响。
PLoS One. 2015 Apr 7;10(4):e0120429. doi: 10.1371/journal.pone.0120429. eCollection 2015.
2
Phase II study of 4-ipomeanol, a naturally occurring alkylating furan, in patients with advanced hepatocellular carcinoma.对晚期肝细胞癌患者进行的4-异戊烯醇（一种天然存在的烷基化呋喃）的II期研究。
Invest New Drugs. 2001;19(1):69-76. doi: 10.1023/a:1006408803734.
3
The role of toxicological interactions in lung injury.
毒理学相互作用在肺损伤中的作用。
Environ Health Perspect. 1984 Apr;55:139-48. doi: 10.1289/ehp.8455139.
4
Mechanism of protection against pneumotoxicity caused by O,S,S-trimethyl phosphorodithioate.O,S,S-三甲基二硫代磷酸酯所致肺毒性的防护机制
Arch Environ Contam Toxicol. 1986 Jan;15(1):87-96. doi: 10.1007/BF01055253.