• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Whole body plethysmography as a noninvasive assay of toxic lung injury in mice: studies with the pulmonary alkylating agent and cytotoxin, 4-ipomeanol.

作者信息

Travis E L, Brightwell D, Aiken M, Boyd M R

出版信息

Toxicol Appl Pharmacol. 1982 Nov;66(2):193-200. doi: 10.1016/0041-008x(82)90284-8.

DOI:10.1016/0041-008x(82)90284-8
PMID:7164098
Abstract
摘要

相似文献

1
Whole body plethysmography as a noninvasive assay of toxic lung injury in mice: studies with the pulmonary alkylating agent and cytotoxin, 4-ipomeanol.全身体积描记法作为小鼠中毒性肺损伤的非侵入性检测方法：使用肺部烷基化剂和细胞毒素4-异戊烯醇的研究
Toxicol Appl Pharmacol. 1982 Nov;66(2):193-200. doi: 10.1016/0041-008x(82)90284-8.
2
In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol.关于靶器官烷基化与4-异戊烯醇化学反应性代谢物肺毒性之间关系的体内研究。
J Pharmacol Exp Ther. 1978 Dec;207(3):687-97.
3
Distribution and metabolism of the pulmonary alkylating agent and cytotoxin, 4-ipomeanol, in control and diethylmaleate-treated rats.
Biochem Pharmacol. 1982 Apr 15;31(8):1585-9. doi: 10.1016/0006-2952(82)90384-7.
4
Development of tolerance to the pulmonary toxin, 4-ipomeanol.对肺部毒素4-异戊二烯醇的耐受性发展
Toxicology. 1981;19(2):85-100. doi: 10.1016/0300-483x(81)90091-3.
5
Protective role of endogenous pulmonary glutathione and other sulfhydryl compounds against lung damage by alkylating agents. Investigations with 4-ipomeanol in the rat.内源性肺谷胱甘肽及其他巯基化合物对烷基化剂所致肺损伤的保护作用。用4-异亚丙基丙酮对大鼠进行的研究。
Biochem Pharmacol. 1982 Apr 15;31(8):1579-83. doi: 10.1016/0006-2952(82)90383-5.
6
Species and strain differences in target organ alkylation and toxicity by 4-ipomeanol. Predictive value of covalent binding in studies of target organ toxicities by reactive metabolites.
Biochem Pharmacol. 1979 Dec 1;28(23):3367-72. doi: 10.1016/0006-2952(79)90074-1.
7
Effect of carbon monoxide on the cytochrome P-450-mediated activation of 4-ipomeanol by the isolated perfused rabbit lung.一氧化碳对离体灌注兔肺中细胞色素P-450介导的4-异蒲勒醇活化作用的影响。
J Toxicol Environ Health. 1989;27(3):341-50. doi: 10.1080/15287398909531305.
8
The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol.兔肺细胞色素P-450同工酶的催化活性与呋喃衍生物4-异戊烯醇的肺特异性毒性之间的关系。
Mol Pharmacol. 1982 Nov;22(3):738-44.
9
Preclinical toxicology studies of 4-ipomeanol: a novel candidate for clinical evaluation in lung cancer.4-异戊烯基甲醇的临床前毒理学研究：肺癌临床评估的新型候选物
Cancer Treat Rep. 1987 Dec;71(12):1157-64.
10
Generation and characterization of a Cyp4b1 null mouse and the role of CYP4B1 in the activation and toxicity of Ipomeanol.Cyp4b1 基因敲除小鼠的构建及其在 Ipomeanol 激活和毒性中的作用。
Toxicol Sci. 2013 Aug;134(2):243-50. doi: 10.1093/toxsci/kft123. Epub 2013 Jun 7.

引用本文的文献

1
Assessment of pulmonary and hematologic toxicities of liblomycin, a novel bleomycin analog.新型博来霉素类似物利布洛霉素的肺毒性和血液学毒性评估。
Invest New Drugs. 1990 Feb;8(1):33-41. doi: 10.1007/BF00216922.