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[从仓鼠(黑线仓鼠)分离出的病毒感染狐狸和猫后实验性狂犬病感染的发病机制]

[Pathogenesis of experimental rabies infection in foxes and cats infected with viruses isolated from hamsters (Cricetus cricetus)].

作者信息

Alexander R, Svrcek S, Vrtiak O J, Ondrejka R, Benísek Z, Závadová J

出版信息

Vet Med (Praha). 1981 Apr;26(4):233-46.

PMID:6791357
Abstract

All the infected foxes (9) contracted the disease and died from rabies the 20th-21st day from infection with the virus isolated from hamster. Out of the total number of 9 cats experimentally infected by intramuscular infection, seven showed symptoms of clinical disease on the 18th-34th day from infection. The infected dogs, wolves and rabbits did not show clinical disease. In the post mortem examination of eight foxes the rabies virus or rabies antigen was detected in all parts of the CNS and in n. ischiadicus. Of the extraneural organs, the virus was present, in all animals, in the pharyngeal salivary glands, and in one fox also in the tongue. The bioassay on the eye was positive in all cases. The rabies antigen was detected in 4 foxes in the thigh muscle, in liver and spleen, and in all 8 foxes in lungs and cornea, in 5 cases in kidney, and in 3 cases in heart and tongue. Seven cats were examined post mortem by the inoculation test on mice and the PMIF-staining test; it was found that the rabies virus, or rabies antigen, was distributed in the same manner as in foxes.

摘要

所有受感染的狐狸(9只)均感染了疾病,并在感染从仓鼠分离出的病毒后的第20至21天死于狂犬病。在通过肌肉注射实验感染的9只猫中,7只在感染后的第18至34天出现了临床疾病症状。受感染的狗、狼和兔子未表现出临床疾病。在对8只狐狸进行的尸检中,在中枢神经系统的所有部位以及坐骨神经中均检测到狂犬病病毒或狂犬病抗原。在神经外器官中,所有动物的咽唾液腺中均存在该病毒,一只狐狸的舌头中也存在该病毒。眼部生物测定在所有病例中均呈阳性。在4只狐狸的大腿肌肉、肝脏和脾脏中检测到狂犬病抗原,在所有8只狐狸的肺部和角膜中检测到狂犬病抗原,5例在肾脏中检测到,3例在心脏和舌头中检测到。对7只猫进行了小鼠接种试验和PMIF染色试验的尸检;发现狂犬病病毒或狂犬病抗原的分布方式与狐狸相同。

相似文献

1
[Pathogenesis of experimental rabies infection in foxes and cats infected with viruses isolated from hamsters (Cricetus cricetus)].[从仓鼠(黑线仓鼠)分离出的病毒感染狐狸和猫后实验性狂犬病感染的发病机制]
Vet Med (Praha). 1981 Apr;26(4):233-46.
2
[Rabies in the common hamster (Cricetus cricetus) in Slovakia].[斯洛伐克普通仓鼠(黑线仓鼠)中的狂犬病]
Vet Med (Praha). 1984 Nov;29(11):643-52.
3
[Distribution of rabies antigen in the central nervous system of rats and mice experimentally infected with rabies strains isolated from hamsters (Cricetus cricetus)].[从仓鼠(黑线仓鼠)分离的狂犬病病毒株实验性感染大鼠和小鼠后狂犬病抗原在其中枢神经系统中的分布]
Vet Med (Praha). 1981 May;26(5):271-8.
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[Peroral infection with rabies virus in fox and domestic cat].[狐狸和家猫经口感染狂犬病病毒]
Acta Vet Acad Sci Hung. 1980;28(1):27-32.
5
Prevalence of rabies virus in foxes trapped in the Canadian Arctic.加拿大北极地区捕获狐狸中狂犬病病毒的流行情况。
Can Vet J. 1980 Nov;21(11):297-300.
6
Experimentally induced rabies in four cats inoculated with a rabies virus isolated from a bat.用从一只蝙蝠分离出的狂犬病病毒对四只猫进行实验性诱发狂犬病。
Am J Vet Res. 1986 Apr;47(4):777-80.
7
Pantropism of rabies virus in free-ranging rabid red fox Vulpes fulva.狂犬病病毒在野生狂犬病赤狐(Vulpes fulva)中的泛嗜性。
J Wildl Dis. 1970 Oct;6(4):500-6. doi: 10.7589/0090-3558-6.4.500.
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Rabies: doubtful and discordant results in fluorescent antibody test.狂犬病:荧光抗体试验结果存疑且不一致。
Med Pregl. 2001;54 Suppl 1:29-31.
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[Distribution of the rabies virus in the central nervous system of naturally infected foxes].[狂犬病病毒在自然感染狐狸中枢神经系统中的分布]
Vet Med (Praha). 1978 Jun;23(6):369-76.
10
Use of monoclonal antibodies to confirm vaccine-induced rabies in ten dogs, two cats, and one fox.使用单克隆抗体在十只狗、两只猫和一只狐狸中确认疫苗诱导的狂犬病。
J Am Vet Med Assoc. 1984 Aug 1;185(3):285-8.

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