Koepchen H P, Klüssendorf D, Sommer D
J Auton Nerv Syst. 1981 Apr;3(2-4):335-68. doi: 10.1016/0165-1838(81)90074-6.
This paper is comprised of a review of past contributions and their theoretical consequences and a presentation of new results in studies of the origin of sympathetic rhythms and tone. Two basic mechanisms are involved: a primary intracentral coupling with the main cardiovascular-respiratory rhythm (MCRR) generator and a secondary reflex coupling. It was found that the activity and rhythms of certain sympathetic efferents, such as the cervical sympathetic, are closely related to the MCRR. Other efferents, such as the renal sympathetics, are loosely linked and follow drives from other circuits in the genesis of their rhythms and tone. New experimental evidence is given that rhythmic and tonic activity in sympathetic nerves originates from several sources. Hence central respiratory-autonomic systems interaction is not explained by simplistic concepts.
本文包括对过去研究成果及其理论影响的综述,以及交感神经节律和张力起源研究中的新结果展示。涉及两种基本机制:与主要心血管 - 呼吸节律(MCRR)发生器的初级中枢内耦合和次级反射耦合。研究发现,某些交感传出神经的活动和节律,如颈交感神经,与MCRR密切相关。其他传出神经,如肾交感神经,联系较松散,在其节律和张力的产生中遵循其他回路的驱动。文中给出了新的实验证据,表明交感神经的节律性和紧张性活动源于多个来源。因此,中枢呼吸 - 自主神经系统的相互作用不能用简单的概念来解释。