联合多胺生物合成抑制剂和S期特异性药物对转化细胞进行选择性杀伤。 - Suppr

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超能文献

Selective killing of transformed cells in combination with inhibitors of polyamine biosynthesis and S-phase specific drugs.

作者信息

Sunkara P S, Fowler S K, Nishioka K

出版信息

Cell Biol Int Rep. 1981 Oct;5(10):991-7. doi: 10.1016/0309-1651(81)90217-4.

DOI:10.1016/0309-1651(81)90217-4

PMID:6793243

Abstract

摘要

相似文献

Selective killing of transformed cells in combination with inhibitors of polyamine biosynthesis and S-phase specific drugs.联合多胺生物合成抑制剂和S期特异性药物对转化细胞进行选择性杀伤。

Cell Biol Int Rep. 1981 Oct;5(10):991-7. doi: 10.1016/0309-1651(81)90217-4.

Inhibition of polyamine biosynthesis by alpha-difluoromethyl ornithine potentiates the cytotoxic effects of arabinosyl cytosine in HeLa cells.α-二氟甲基鸟氨酸对多胺生物合成的抑制作用增强了阿糖胞苷对HeLa细胞的细胞毒性作用。

Biochem Biophys Res Commun. 1980 Jul 16;95(1):423-30. doi: 10.1016/0006-291x(80)90755-x.

Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.多胺生物合成受抑制后大鼠肝癌组织培养细胞中多胺含量的恢复。与细胞增殖的关系。

Eur J Biochem. 1986 Apr 1;156(1):31-5. doi: 10.1111/j.1432-1033.1986.tb09544.x.

Polyamine biosynthetic enzymes as targets in cancer chemotherapy.多胺生物合成酶作为癌症化疗的靶点。

Adv Enzyme Regul. 1984;22:243-64. doi: 10.1016/0065-2571(84)90017-7.

Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.用D，L-α-二氟甲基鸟氨酸处理使9L大鼠脑肿瘤细胞的多胺含量耗竭，可抑制细胞增殖及G1期到S期的转变。

Exp Cell Res. 1981 Jan;131(1):209-16. doi: 10.1016/0014-4827(81)90420-1.

Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.多胺生物合成与皮肤肿瘤促进作用：鸟氨酸脱羧酶不可逆抑制剂α-二氟甲基鸟氨酸对12-O-十四烷酰佛波醇-13-乙酸酯促进的小鼠皮肤肿瘤形成的抑制作用

Biochem Biophys Res Commun. 1982 Apr 14;105(3):969-76. doi: 10.1016/0006-291x(82)91065-8.

The role of polyamine depletion and accumulation of decarboxylated S-adenosylmethionine in the inhibition of growth of SV-3T3 cells treated with alpha-difluoromethylornithine.多胺耗竭和脱羧S-腺苷甲硫氨酸的积累在α-二氟甲基鸟氨酸处理的SV-3T3细胞生长抑制中的作用

Biochem J. 1984 Nov 15;224(1):29-38. doi: 10.1042/bj2240029.

Role of polyamines in HeLa cell proliferation.多胺在HeLa细胞增殖中的作用。

Med Biol. 1981 Dec;59(5-6):410-6.

Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).α-甲基鸟氨酸与甲基乙二醛双（脒腙）联合使用对活化淋巴细胞中多胺和DNA合成的抑制作用

Cancer Res. 1977 Sep;37(9):3169-72.

The chemotherapeutic potential of polyamine antimetabolites.多胺抗代谢物的化疗潜力。

Ann R Coll Surg Engl. 1986 Mar;68(2):76-81.

引用本文的文献

Polyamine-DNA Interactions: Possible Site of New Cancer Chemotherapeutic Intervention.多胺与 DNA 的相互作用：新的癌症化学治疗干预的可能靶点。

Pharm Res. 1986 Dec;3(6):311-7. doi: 10.1023/A:1016375705487.

Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines.两种多胺类似物（BE-4-4-4和BE-4-4-4-4）直接影响两种人脑肿瘤细胞系的生长、存活及细胞周期进程。

Cancer Chemother Pharmacol. 1995;36(5):411-7. doi: 10.1007/BF00686190.

Polyamine cytochemistry. Use of a novel o-phtalaldehyde method for visualizing spermidine and spermine. Comparisons to the formaldehyde-fluorescamine method.

Histochemistry. 1982;76(2):247-59. doi: 10.1007/BF00501927.

Polyamines in clinical disorders.临床疾病中的多胺

West J Med. 1985 Jan;142(1):63-73.

Phase I evaluation of intravenous difluoromethylornithine--a polyamine inhibitor.静脉注射二氟甲基鸟氨酸（一种多胺抑制剂）的I期评估

Invest New Drugs. 1985;3(3):287-92. doi: 10.1007/BF00179433.

Schedule dependent potentiation of antitumor drug effects by alpha-difluoromethylornithine in human gastric carcinoma cells in vitro.α-二氟甲基鸟氨酸在体外人胃癌细胞中对抗肿瘤药物作用的时间依赖性增强

Invest New Drugs. 1990;8 Suppl 1:S9-18. doi: 10.1007/BF00171979.

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