Lebedev A A, Posokhov V P
Farmakol Toksikol. 1981 May-Jun;44(3):309-14.
The effect of novurit, mannitol and furosemide on permeability of the intercellular interstice of the frog urinary bladder by inulin, saccharose, iodide, lithium cation and fluorescein moving against a concentration gradient was examined. Novurit (0.5--6 mM/l) raised permeability of the intercellular interstice by all test substances and ions. Mannitol (210 mM/l) increased permeability of the intercellular interstice by lithium cation and fluorescein, while furosemide failed to exert any effect on permeability. The character of asymmetrical ionic flows moving in opposite directions across the wall of the frog urinary bladder is discussed.
研究了诺呋利、甘露醇和呋塞米对蛙膀胱细胞间间隙通透性的影响，通过检测菊粉、蔗糖、碘化物、锂离子和荧光素逆浓度梯度移动情况进行研究。诺呋利（0.5 - 6 mM/l）可提高所有受试物质和离子通过细胞间间隙的通透性。甘露醇（210 mM/l）可增加锂离子和荧光素通过细胞间间隙的通透性，而呋塞米对通透性无任何影响。讨论了蛙膀胱壁两侧方向相反的不对称离子流的特征。
