Wilson L A, Schlitzer R L, Ahearn D G
Am J Ophthalmol. 1981 Oct;92(4):546-54. doi: 10.1016/0002-9394(81)90649-8.
Seven Pseudomonas corneal ulcers in six patients were associated with soft contact-lens wear and use of saline solutions prepared from distilled water and sodium chloride tablets. The same species of Pseudomonas isolated from the corneal ulcers were also isolated from the home-prepared saline and in one instance from the water used to prepare the saline solution. In three of the six patients, the pseudomonad isolated from the corneal ulcer was of the same serotype and biochemically identical to the pseudomonad from the patients' saline solution. Commercially available distilled water, even brands recommended for use with soft contact lenses, was found to be contaminated with gram-negative bacteria before use. Clinical histories disclosed that all patients inappropriately used the home-prepared saline as a wetting agent, or eyedrop, or bath, after thermal disinfection of the contact lens. Self-inoculation of the eye with contaminated saline is a hazard for soft contact-lens wearers who use home-prepared saline solution.
6名患者的7例铜绿假单胞菌角膜溃疡与软性隐形眼镜佩戴以及使用由蒸馏水和氯化钠片配制的盐溶液有关。从角膜溃疡中分离出的铜绿假单胞菌与自制盐溶液中分离出的相同菌种相同，在一个病例中还与用于配制盐溶液的水中分离出的菌种相同。在6名患者中的3名患者中，从角膜溃疡中分离出的假单胞菌与患者盐溶液中的假单胞菌血清型相同且生化特性相同。发现市售蒸馏水，即使是推荐用于软性隐形眼镜的品牌，在使用前也被革兰氏阴性细菌污染。临床病史显示，所有患者在对隐形眼镜进行热消毒后，都不恰当地将自制盐溶液用作湿润剂、眼药水或洗眼液。对于使用自制盐溶液的软性隐形眼镜佩戴者来说，被污染的盐溶液自我接种到眼睛是一种危险。
