酮症和乳酸酸中毒患者尿液中2-羟基丁酸的绝对构型。

The absolute configuration of urinary 2-hydroxybutyric acid in patients with ketosis and lactic acidosis.

作者信息

Kamerling J P, Gerwig G J, Duran M, Ketting D, Wadman S K

出版信息

Clin Chim Acta. 1978 Aug 15;88(1):183-8. doi: 10.1016/0009-8981(78)90168-7.

Abstract

The absolute configurations of urinary 2-hydroxybutyrate and 3-hydroxybutyrate were determined in patients with lactic acidemia and ketosis by capillary gas-liquid chromatography of their O-acetylated (--)-menthyl ester derivatives. 2-Hydroxybutyrate had the L-configuration, whereas 3-hydroxybutyrate was in the D-configuration.

摘要

通过对乳酸血症和酮症患者尿液中2-羟基丁酸和3-羟基丁酸的O-乙酰化（-）-薄荷酯衍生物进行毛细管气液色谱分析，确定了它们的绝对构型。2-羟基丁酸具有L-构型，而3-羟基丁酸为D-构型。