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Determination of the configurations of lactic and glyceric acids from human serum and urine by capillary gas-liquid chromatography.

作者信息

Kamerling J P, Gerwig G J, Vliegenthart J F

出版信息

J Chromatogr. 1977 Mar 1;143(2):117-23. doi: 10.1016/s0378-4347(00)81817-4.

DOI:10.1016/s0378-4347(00)81817-4
PMID:838825
Abstract

The separation of the enantiomers of lactic and glyceric acids can be achieved by capillary gas chromatography on SP-1000 using the corresponding O-acetylated methyl esters. The structures of the derivatives were proved by proton magnetic resonance spectroscopy and mass spectrometry. The method has been used for the determination of the absolute configuration of lactic and glyceric acids isolated from serum and urine from different patients.

摘要

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引用本文的文献

1
A new case of hyperoxaluria type II.一例新的II型高草酸尿症病例。
J Inherit Metab Dis. 1993;16(5):896-7. doi: 10.1007/BF00714287.
2
L-2-Hydroxyglutaric aciduria: an inborn error of metabolism?L-2-羟基戊二酸尿症：一种先天性代谢缺陷病？
J Inherit Metab Dis. 1980;3(4):109-12. doi: 10.1007/BF02312543.
3
D-2-hydroxyglutaric aciduria: case report and biochemical studies.D-2-羟基戊二酸尿症：病例报告及生化研究
J Inherit Metab Dis. 1980;3(1):11-5. doi: 10.1007/BF02312516.
4
Excessive excretion of beta-alanine and of 3-hydroxypropionic, R- and S-3-aminoisobutyric, R- and S-3-hydroxyisobutyric and S-2-(hydroxymethyl)butyric acids probably due to a defect in the metabolism of the corresponding malonic semialdehydes.β-丙氨酸、3-羟基丙酸、R-和S-3-氨基异丁酸、R-和S-3-羟基异丁酸以及S-2-(羟甲基)丁酸排泄过多，可能是由于相应丙二酸半醛代谢缺陷所致。
J Inherit Metab Dis. 1985;8(2):75-9. doi: 10.1007/BF01801669.
5
Primary hyperoxaluria and L-glyceric aciduria in the cat.猫的原发性高草酸尿症和L-甘油酸尿症
J Inherit Metab Dis. 1988;11 Suppl 2:215-7. doi: 10.1007/BF01804239.
6
Determination of optical isomers in patients with organic aciduria.有机酸尿症患者光学异构体的测定。
J Inherit Metab Dis. 1978;1(1):17. doi: 10.1007/BF01805709.