von Lüdinghausen M, von Lüdinghausen E, Anastasiadis P
MMW Munch Med Wochenschr. 1981 Nov 6;123(45):1699-704.
In cytological impression preparations of the endometrium practically only superficial epithelia were obtained and evaluated. In half of the sexually mature and premenopausal women a corresponding secretory change was found in the middle or in the late luteal phase only. Atypical surface epithelia are only to be observed at the beginning of the proliferation phase, in regeneration after abrasion, in chronic endometritis, with a fitted intrauterine pessary, estrogen therapy and in pregnancy and may lead to false positive results. In postmenopausal women a third of glandular hyperplasias with exuberant growth in the depths of the mucosa show superficial resting or only a few active epithelial cells which may lead to underestimation of the results, occasionally, in the case of an incipient well-differentiated carcinoma even to a false negative assessment.
在子宫内膜的细胞学印片制备中,实际上仅获取并评估了表层上皮。在一半性成熟和绝经前的女性中,仅在黄体中期或晚期发现了相应的分泌变化。非典型表面上皮仅在增殖期开始时、刮宫后再生时、慢性子宫内膜炎时、使用合适的宫内节育器时、雌激素治疗时以及妊娠时可见,可能导致假阳性结果。在绝经后女性中,三分之一的黏膜深层有旺盛生长的腺体增生显示表层静止或仅有少数活跃上皮细胞,这可能导致结果低估,在早期高分化癌的情况下偶尔甚至会导致假阴性评估。