植物中乙酰胆碱的合成。
The synthesis of acetylcholine by plants.
作者信息
Smallman B N, Maneckjee A
出版信息
Biochem J. 1981 Jan 15;194(1):361-4. doi: 10.1042/bj1940361.
Abstract
Choline acetyltransferase was demonstrated in nettles (Urtica dioica), peas (Pisum sativum), spinach (Spinacia oleracea), sunflower (Helianthus annuus) and blue--green algae by using a Sepharose--CoASH affinity column. The column effected a 1500-fold purification of the enzyme from nettle homogenates and was required for demonstrating activity in the other higher plants. Demonstration of the enzyme in blue-green algae suggests that acetylcholine was a biochemical necessity in the earliest photosynthetic organisms.
摘要
通过使用琼脂糖 - 辅酶A亲和柱，在荨麻（异株荨麻）、豌豆（豌豆）、菠菜（菠菜）、向日葵（向日葵）和蓝藻中证实了胆碱乙酰转移酶的存在。该柱对荨麻匀浆中的这种酶进行了1500倍的纯化，并且对于证明其他高等植物中的活性是必需的。在蓝藻中证明这种酶表明乙酰胆碱在最早的光合生物中是一种生化必需品。
相似文献
1
The synthesis of acetylcholine by plants.植物中乙酰胆碱的合成。
Biochem J. 1981 Jan 15;194(1):361-4. doi: 10.1042/bj1940361.
2
Choline acetyltransferase in the nettle Urtica dioica L.荨麻（Urtica dioica L.）中的胆碱乙酰转移酶
Biochem J. 1973 Jan;132(1):15-8. doi: 10.1042/bj1320015.
3
Acetylcholine synthesizing enzymes in frog skeletal muscle.青蛙骨骼肌中的乙酰胆碱合成酶。
J Neurochem. 1980 Nov;35(5):1021-5. doi: 10.1111/j.1471-4159.1980.tb07855.x.
4
Enzymic synthesis of sym-homospermidine in Lathyrus sativus (grass pea) seedlings.山黧豆（草豌豆）幼苗中对称高亚精胺的酶促合成
Biochem J. 1980 Aug 15;190(2):461-4. doi: 10.1042/bj1900461.
5
The synthesis of acetylcholine: twenty years of progress.乙酰胆碱的合成：二十年的进展
Prog Brain Res. 1990;84:467-77.
6
Acetylcholine synthesis by choline acetyltransferase of a peripheral type as demonstrated in adult rat dorsal root ganglion.成年大鼠背根神经节中所证实的外周型胆碱乙酰转移酶合成乙酰胆碱。
J Neurochem. 2007 Jun;101(6):1607-18. doi: 10.1111/j.1471-4159.2007.04458.x.
7
Choline acetyltransferase activity bound to synaptosomal plasma membranes as regulatory step in acetylcholine biosynthesis.
Acta Neurol (Napoli). 1988 Apr;10(2):85-92.
8
Supply of acetylcoenzyme A and choline acetyltransferase for acetylcholine synthesis in cholinergic nerve endings.
Act Nerv Super (Praha). 1976 Jun;18(1-2):109-10.
9
[Assessment of the activity of choline acetyltransferase in heart tissues].[心脏组织中胆碱乙酰转移酶活性的评估]
Vopr Med Khim. 1993 Jan-Feb;39(1):25-9.
10
Effects of vitamin B12 supplementation on choline acetyltransferase activity in cat brain.补充维生素B12对猫脑胆碱乙酰转移酶活性的影响。
Int J Vitam Nutr Res. 1988;58(4):402-6.
引用本文的文献
1
Butyrylcholinesterase distribution in the mouse gastrointestinal tract: An immunohistochemical study.丁酰胆碱酯酶在小鼠胃肠道中的分布：免疫组织化学研究。
J Anat. 2023 Feb;242(2):245-256. doi: 10.1111/joa.13754. Epub 2022 Aug 25.
2
Influence of acetylcholine agonists and antagonists on the swelling of etiolated wheat (Triticum aestivum L.) mesophyll protoplasts.乙酰胆碱激动剂和拮抗剂对黄化小麦（Triticum aestivum L.）叶肉原生质体肿胀的影响。
Planta. 1990 Nov;182(4):473-9. doi: 10.1007/BF02341020.
3
Production and functional expression of an epitope-tagged human choline acetyltransferase.一种表位标记的人胆碱乙酰转移酶的产生及功能表达。
J Mol Neurosci. 1998 Dec;11(3):243-51. doi: 10.1385/JMN:11:3:243.
本文引用的文献
1
The mechanism of the sting of the common nettle (urtica urens).普通荨麻（荨麻属）蜇刺的机制。
J Physiol. 1947 Oct 15;106(4):440-55. doi: 10.1113/jphysiol.1947.sp004225.
2
Mechanisms of acetylcholine synthesis in the blowfly.家蝇中乙酰胆碱的合成机制。
J Physiol. 1956 May 28;132(2):343-57. doi: 10.1113/jphysiol.1956.sp005527.
3
Acetylcholinesterase hydrolysis of halogen substituted acetylcholines.卤素取代乙酰胆碱的乙酰胆碱酯酶水解作用
Biochem Pharmacol. 1968 May;17(5):805-15. doi: 10.1016/0006-2952(68)90017-8.
4
Evidence for the regulation of phytochrome-mediated processes in bean roots by the neurohumor, acetylcholine.神经体液乙酰胆碱对菜豆根中光敏色素介导过程的调节作用的证据。
Plant Physiol. 1970 Dec;46(6):768-77. doi: 10.1104/pp.46.6.768.
5
The kinetic properties of human placental choline acetyltransferase.人胎盘胆碱乙酰转移酶的动力学特性
Biochem J. 1971 Dec;125(3):857-63. doi: 10.1042/bj1250857.
6
Choline acetyltransferase in the nettle Urtica dioica L.荨麻（Urtica dioica L.）中的胆碱乙酰转移酶
Biochem J. 1973 Jan;132(1):15-8. doi: 10.1042/bj1320015.
7
Measurement and activation of choline acetyltransferase.胆碱乙酰转移酶的测定与激活
Biochem Pharmacol. 1975 May 1;24(9):1007-11. doi: 10.1016/0006-2952(75)90437-2.
8
A rapid radiochemical method for the determination of choline acetyltransferase.一种用于测定胆碱乙酰转移酶的快速放射化学方法。
J Neurochem. 1975 Feb;24(2):407-9. doi: 10.1111/j.1471-4159.1975.tb11895.x.
Zotero 插件