铜对可翻译的金属硫蛋白信使核糖核酸的诱导作用。
Copper induction of translatable metallothionein messenger RNA.
作者信息
Mercer J F, Lazdins I, Stevenson T, Camakaris J, Danks D M
出版信息
Biosci Rep. 1981 Oct;1(10):793-800. doi: 10.1007/BF01114802.
PMID:6796153
Abstract
Copper chloride injection of rats resulted in a 4.5- to 9-fold increase in translatable metallothionein messenger RNA in the liver. Metallothionein in the translation products was identified on the basis of high cysteine and serine incorporation and absence of leucine incorporation as well as comigration with authentic zinc-induced rat-liver metallothionein on SDS-polyacrylamide gels.
摘要
给大鼠注射氯化铜后，其肝脏中可翻译的金属硫蛋白信使核糖核酸增加了4.5至9倍。根据翻译产物中高半胱氨酸和丝氨酸掺入、亮氨酸不掺入以及在十二烷基硫酸钠-聚丙烯酰胺凝胶上与真正的锌诱导大鼠肝脏金属硫蛋白共同迁移的情况，鉴定出了翻译产物中的金属硫蛋白。
Zotero 插件