Taylor R G, Crisp A J, Hoffbrand B I, Maguire A, Jacobs H S
Postgrad Med J. 1981 Jul;57(669):425-6. doi: 10.1136/pgmj.57.669.425.
Serum concentrations of LH, FSH, testosterone and prolactin were measured in patients with hypertension treated with propranolol (34 cases), methyldopa (13 cases), and methyldopa + propranolol (11 cases). The results were compared with those obtained in 18 controls (hospital out-patients). There were no differences in these hormone concentrations in the various groups, and no difference between those complaining of impotence (13 cases) and those with normal sexual function. Impotence in hypertensive men on treatment with methyldopa cannot be explained by abnormalities in secretion of the reproductive hormones.
对接受普萘洛尔治疗的高血压患者(34例)、甲基多巴治疗的高血压患者(13例)以及甲基多巴 + 普萘洛尔联合治疗的高血压患者(11例)测定血清促黄体生成素(LH)、促卵泡生成素(FSH)、睾酮和催乳素浓度。将结果与18名对照者(医院门诊患者)的结果进行比较。各组间这些激素浓度无差异,主诉阳痿的患者(13例)与性功能正常的患者之间也无差异。服用甲基多巴治疗的高血压男性出现的阳痿不能用生殖激素分泌异常来解释。