A retrospective study of immunoglobulin treatment as part of a multi-factorial therapy in children with acute lymphatic leukemia.

During the multifactorial treatment of acute lymphatic leukemia (ALL) bacterial and viral secondary infections are rather common due to the therapeutic immunosuppression. For prophylactic reasons the administration of i.v. tolerable immunoglobulins is indicated during the course of the leukemia treatment. In a retrospective study the acute tolerance of an IgG-preparation (Intraglobin) in 56 children suffering from ALL was investigated. On the average each child received 6 applications (total number: 361) within a maximum observation treatment period of 7 years. Only in three cases minor side-effects were observed which corresponds to a reaction rate of less than 1%.