Azin A L
Fiziol Zh SSSR Im I M Sechenova. 1981 Nov;67(11):1652-60.
The O2 insufficiency and excessive CO2 relaxed the brain arteries smooth muscles abolishing their spontaneous electrical and contractile activity. The hypoxia effects were potentiated in the hypopotassium milieu and weakened in the hyperpotassium and hyposodium solutions. Hypercapnic responses insignificantly both in hypo- and hyperpotassium solutions whereas hyposodium one enhanced them. A decrease of the extracellular PO2 seems to reduce the excitability of membranes and to inhibit the active transport of Na+ and K+. CO2 appears to exert no considerable effect on the active transport processes but to interfere in the intracellular mechanisms of Ca2+ regulation.
氧气不足和二氧化碳过多会使脑动脉平滑肌松弛，消除其自发的电活动和收缩活动。在低钾环境中，缺氧效应增强，而在高钾和低钠溶液中则减弱。在低钾和高钾溶液中，高碳酸血症反应不明显，而低钠溶液则增强了这种反应。细胞外氧分压的降低似乎会降低膜的兴奋性，并抑制钠和钾的主动转运。二氧化碳似乎对主动转运过程没有显著影响，但会干扰细胞内钙调节机制。
