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Effects of porcine follicular fluid on gonadotropin concentrations in rhesus monkeys.

作者信息

Rettori V, Siler-Khodr T M, Pauerstein C J, Smith C G, Asch R H

出版信息

J Clin Endocrinol Metab. 1982 Mar;54(3):500-3. doi: 10.1210/jcem-54-3-500.

DOI:10.1210/jcem-54-3-500
PMID:6799538
Abstract

The administration of steroid-free charcoal-treated porcine follicular fluid to long term castrated female rhesus monkeys lowered basal serum concentrations of FSH and had almost no effect on serum LH. Treatment with porcine follicular fluid before the administration of exogenous LRH inhibited the release of FSH, but also affected the release of LH. This inhibition was especially striking on the suppression of the peak of release of both FSH or LH at 20 min. These findings suggest that an inhibin-like material present in follicular fluid could play an important role in the secretion of FSH and LH in rhesus monkeys.

摘要

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