Andersen P K, Stokke D B, Hole P, Nielsen H, Rosendal T
Anaesthesist. 1981 Dec;30(12):610-3.
The distribution of arterial carbon dioxide tensions (PaCO2) in 288 anaesthetized, healthy patients in the prone position was investigated during non-monitored manual ventilation. Four equal groups of 72 patients were compared employing a conventional anaesthetic system with and without CO2-absorption and a modified Mapleson D rebreathing system using high and low fresh gas flows. No fundamental difference between the Mapleson D system and the circle system without CO2-absorption could be demonstrated. With the Mapleson D system a high fresh gas flow resulted in a loss of rebreathing characteristics, the scatter of PaCO2-values then approaching that of a conventional circle system with CO2-absorption. The results demonstrate that during manual ventilation a CO2-absorption results in unpredictable levels of PaCO2 with unacceptably wide ranges. On the other hand, prevention of hypocapnia could be obtained with the rebreathing systems using a low fresh gas flow. Hypercapnia was modest and similar in all groups, PaCO2 never exceeding 7.3 kPa. In terms of PaCO2-levels it seems, compared to recent literature, of no importance whether the patient is prone or supine or whether or not ventilation is monitored, performed by hand or by means of anaesthetic ventilators. Accurate levels of PaCO2 can probably only be obtained by frequent analyses of PaCO2, or monitoring of the end-tidal CO2 concentration.
在未监测的手动通气过程中,对288例处于俯卧位的麻醉健康患者的动脉二氧化碳分压(PaCO₂)分布情况进行了研究。采用有和没有二氧化碳吸收装置的传统麻醉系统以及使用高、低新鲜气体流量的改良Mapleson D再呼吸系统,对四组每组72例患者进行了比较。结果表明,Mapleson D系统与没有二氧化碳吸收装置的循环系统之间没有本质区别。使用Mapleson D系统时,高新鲜气体流量会导致再呼吸特性丧失,此时PaCO₂值的离散度接近带有二氧化碳吸收装置的传统循环系统。结果表明,在手动通气期间,二氧化碳吸收会导致PaCO₂水平不可预测,范围宽到令人无法接受。另一方面,使用低新鲜气体流量的再呼吸系统可以预防低碳酸血症。所有组的高碳酸血症程度较轻且相似,PaCO₂从未超过7.3kPa。就PaCO₂水平而言,与最近的文献相比,患者是俯卧还是仰卧,以及通气是否受到监测、是手动进行还是通过麻醉呼吸机进行,似乎都无关紧要。准确的PaCO₂水平可能只能通过频繁分析PaCO₂或监测呼气末二氧化碳浓度来获得。