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通过一份血浆样本测定51铬-乙二胺四乙酸清除率。

51Cr-EDTA clearance determined by one plasma sample.

作者信息

Groth S, Aasted M

出版信息

Clin Physiol. 1981 Aug;1(4):417-25. doi: 10.1111/j.1475-097x.1981.tb00909.x.

DOI:10.1111/j.1475-097x.1981.tb00909.x
PMID:6800683
Abstract

51Cr-EDTA clearance was measured in 99 consecutive patients. Based on the individual plasma activity at 180, 200, 220, and 240 min after injection (normalized with respect to injected dose/body surface area), a nomogram and a formula were derived for the relation between clearance and the plasma activity in one sample drawn between 180 and 240 min after injection. The nomogram was tested by the activity in 141 plasma nomogram were compared to the corresponding clearance value calculated by a conventional standard method. The correlation coefficient for this comparison was r = 0.982. It is recommended that the nomogram should only be used if clearance values above 30 ml/min are expected.

摘要

对99例连续患者进行了51Cr-乙二胺四乙酸清除率测定。根据注射后180、200、220和240分钟时的个体血浆活性(相对于注射剂量/体表面积进行标准化),得出了一个列线图和一个公式,用于描述注射后180至240分钟之间采集的一个样本中清除率与血浆活性之间的关系。通过141份血浆样本的活性对该列线图进行了测试,并将列线图结果与通过传统标准方法计算得到的相应清除率值进行了比较。该比较的相关系数为r = 0.982。建议仅在预期清除率值高于30 ml/min时使用该列线图。

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