禁食和进食大鼠分离的全胃小囊的分泌情况。
Secretions of isolated total gastric pouches in fasting and fed rats.
作者信息
Levan V H, Ghazi A
出版信息
Exp Pathol. 1981;20(4):189-92. doi: 10.1016/s0232-1513(81)80021-7.
In the fasting state, the secretions of isolated total gastric pouches were higher than what was found in classical gastric fistulae. Serum gastrin was lower in operated rats than in normal non-operated rats. The proximal duodenum would contain a substance which inhibited volume and acidity secretion and stimulated pepsin secretion. This role could be developed upon secretin and its family present in high concentration in the upper duodenum. If the vagus was necessary to volume and acid secretion, its action on pepsin secretion was strengthened by the proximal duodenum. After an intestinal meal, all secretions were enhanced, confirming the hypothesis that the intestine would contain an hormone which would act through the vagus, principally for volume and acid secretions and partially for pepsin secretion.
在禁食状态下，孤立的全胃囊的分泌量高于经典胃瘘的分泌量。手术大鼠的血清胃泌素低于正常未手术大鼠。十二指肠近端会含有一种物质，它能抑制容量和酸度分泌并刺激胃蛋白酶分泌。这种作用可能是由十二指肠上部高浓度存在的促胰液素及其家族发挥的。如果迷走神经对容量和酸分泌是必需的，那么它对胃蛋白酶分泌的作用会因十二指肠近端而增强。进食肠内食物后，所有分泌都增强了，这证实了一种假说，即肠道会含有一种激素，它通过迷走神经起作用，主要作用于容量和酸分泌，部分作用于胃蛋白酶分泌。
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