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血清谷草转氨酶/血清谷丙转氨酶比值作为重症急性病毒性肝炎的预后指标

The serum glutamic oxaloacetic transaminase/serum glutamic pyruvic transaminase ratio as a prognostic index in severe acute viral hepatitis.

作者信息

Gitlin N

出版信息

Am J Gastroenterol. 1982 Jan;77(1):2-4.

PMID:6801971
Abstract

The SGOT/SGPT ratio was studied in 25 patients with severe acute viral hepatitis due to either B or non A-non B hepatitis. The transaminase levels were performed within 10 days of onset of the hepatitis or within 4 days of the diagnosis of fulminant hepatic failure. Twelve patients died of their acute illness. There was a significant difference between the SGOT/SGPT ratios of females who died mean = 2.05) and lived (mean 0.45) (p less than 0.001) and between the SGOT/SGPT ratios of males who died (mean - 1.01) and lived (mean 0.45) (p less than 0.02). Using 95% confidence intervals the expected ratios for combined sexes were calculated to be 0.31 to 0.63 for survivors and from 1.20 to 2.26 for nonsurvivors. Neither age not viral etiology affected the prognosis in this study.

摘要

对25例因乙型肝炎或非甲非乙型肝炎导致的严重急性病毒性肝炎患者的谷草转氨酶/谷丙转氨酶(SGOT/SGPT)比值进行了研究。转氨酶水平在肝炎发病后10天内或暴发性肝衰竭诊断后4天内检测。12例患者死于急性疾病。死亡女性(平均2.05)与存活女性(平均0.45)的SGOT/SGPT比值之间存在显著差异(p<0.001),死亡男性(平均1.01)与存活男性(平均0.45)的SGOT/SGPT比值之间也存在显著差异(p<0.02)。使用95%置信区间计算得出,存活者的综合性别预期比值为0.31至0.63,非存活者为1.20至2.26。在本研究中,年龄和病毒病因均不影响预后。

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