Tsinzerling A V, Vydumkina S P
Arkh Patol. 1982;44(1):24-9.
Examinations involved 40 stillborns and infants of up to 3 days of age using light and immunofluorescent (IF) microscopy, and the results obtained were compared with the data of clinical observations and serological examinations of the blood of infants and their mothers. The diagnostic titer of antibody determined by complement fixation and hemagglutination-inhibition tests was higher to respiratory viruses (1--4 in each baby) in 72.5% of babies and to M. pneumoniae in 17.5%. At a high antibody titer indicating a considerable duration of the disease, the results of IF studies were usually negative and the structural changes typical for individual infections of this group were insignificant or absent. This agrees with the results of previous studies of postnatally developing viral infections. At low antibody titres, in a number of cases the results of IF studies were positive and there were structural changes indicating a recent development of the disease. The possibility of antibody formation in fetuses was confirmed by selective studies of globulins in influenza A which proved to be M-globulins.
研究对40例死产儿及出生3天内的婴儿进行了光学显微镜和免疫荧光（IF）显微镜检查，并将所得结果与婴儿及其母亲的临床观察数据和血液血清学检查数据进行了比较。通过补体结合试验和血凝抑制试验确定的抗体诊断滴度，在72.5%的婴儿中针对呼吸道病毒（每个婴儿1 - 4种）较高，在17.5%的婴儿中针对肺炎支原体较高。在表明疾病持续时间较长的高抗体滴度情况下，IF研究结果通常为阴性，该组个别感染典型的结构变化不明显或不存在。这与先前关于产后发生的病毒感染的研究结果一致。在低抗体滴度时，在一些病例中IF研究结果为阳性，且存在表明疾病近期发生的结构变化。对甲型流感球蛋白的选择性研究证实了胎儿体内抗体形成的可能性，结果表明其为M球蛋白。
