Ruckley C V, Thurston C
Br Med J (Clin Res Ed). 1982 Apr 10;284(6322):1100-2. doi: 10.1136/bmj.284.6322.1100.
The Edinburgh surgical statistics (audit) have been analysed for the years 1959, 1964, 1969, 1974, and 1979 to determine the trends in pulmonary embolism in surgical patients who died. There was a total of 61,038 operations, 1528 postoperative deaths, 804 necropsies, and 158 reported pulmonary emboli. The incidence of embolism diagnosed clinically and at necropsy fell throughout the period. This fall held good after corrections for necropsy rates, prognosis, and proportions of major operations. Although the overall necropsy rate fell from 58% to 40%, in patients expected to have a good prognosis the rate rose from 68% to 75%. Necropsy-proved embolism in "good prognosis" patients fell from 0.5% to 0.15% per 100 major operations. The main reduction has taken place since most surgeons in the area adopted methods of prophylaxis against venous thrombosis, but a direct relationship is not proved by this study.
对1959年、1964年、1969年、1974年和1979年的爱丁堡外科手术统计数据(审计资料)进行了分析,以确定死亡外科患者中肺栓塞的发展趋势。共有61038例手术,1528例术后死亡,804例尸检,以及158例报告的肺栓塞病例。在整个时间段内,临床诊断和尸检诊断的栓塞发生率均呈下降趋势。在对尸检率、预后及大手术比例进行校正后,这一下降趋势依然成立。尽管总体尸检率从58%降至40%,但预计预后良好的患者尸检率却从68%升至75%。“预后良好”患者中经尸检证实的栓塞发生率从每100例大手术0.5%降至0.15%。主要的下降发生在该地区大多数外科医生采用预防静脉血栓形成的方法之后,但本研究并未证实二者存在直接关联。