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[组织糖酵解在高碳酸血症、低氧血症和低温联合暴露中的作用]

[Role of tissue glycolysis in combined exposure to hypercapnia, hypoxia and hypothermia].

作者信息

Baev V I, Volkova Z A, Maksimov N A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1978 Jun;64(6):858-63.

PMID:680273
Abstract

The amount of metabolites of the glycolytic way of carbohydrates transformation and the enzymatic activity were studied in the tissues of brain, myocardium, liver, skeletal muscles, and the blood serum of rats subjected to cooling in conditions of gradually increasing concentrations of CO2 and decreasing concentrations of O2. Single as well as repeated actions of these factors entailed changes of the substrates under study and of some enzymatic activity which revealed a moderate intensification of the glycolysis within the general rearrangement of metabolism during adaptation to sharp hypoxia under the above conditions.

摘要

在二氧化碳浓度逐渐升高和氧气浓度逐渐降低的条件下对大鼠进行冷却处理,研究了其脑、心肌、肝脏、骨骼肌组织以及血清中碳水化合物糖酵解转化途径的代谢物量和酶活性。这些因素的单次及重复作用导致了所研究底物和某些酶活性的变化,这表明在上述条件下适应急剧缺氧的代谢总体重排过程中,糖酵解有适度增强。

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