Waitkins S A, Anderson R D
J Clin Pathol. 1982 Feb;35(2):215-8. doi: 10.1136/jcp.35.2.215.
The fluorescent antibody test is now widely used to confirm the identity of Neisseria gonorrhoeae but may fail to identify penicillinase-producing strains (PPNG). This problem arises when conjugates are used that incorporate only gonococci that are not penicillinase-producers. We have shown that conjugates prepared from mixtures of PPNG and non-penicillinase producing gonococci give good fluorescent reactions. This difference in the reactions of PPNG strains is clearly related to their penicillinase-producing abilities, further study of the antigenic relation between penicillinase production and the antigenic structure of N gonorrhoeae is evidently required.
荧光抗体试验目前广泛用于确认淋病奈瑟菌的身份，但可能无法识别产青霉素酶菌株（PPNG）。当使用仅包含非产青霉素酶淋球菌的结合物时，就会出现这个问题。我们已经表明，由PPNG和非产青霉素酶淋球菌的混合物制备的结合物能产生良好的荧光反应。PPNG菌株反应的这种差异显然与其产青霉素酶的能力有关，显然需要进一步研究产青霉素酶与淋病奈瑟菌抗原结构之间的抗原关系。
