Dillon J R, Pauzé M, Jessamine A G
Can Med Assoc J. 1981 Oct 15;125(8):851-5.
The incidence of infection with penicillinase-producing Neisseria gonorrhoeae (PPNG) reported to the Laboratory Centre for Disease Control in Ottawa has steadily increased since the first Canadian isolation of such a strain in 1976. As of September 1980 a total of 66 PPNG isolates had been referred for biological and genetic characterization as well as for central documentation of the epidemiologic aspects of each case. Over 90% of the infections were firmly traced to patients or contacts who had acquired the infection abroad; this indicates that Canada does not, as yet, have an epidemic focus of PPNG infection. This report includes a synopsis of the biological characteristics of these isolates and an analysis of the results of primary antibiotic treatment that illustrates the importance of considering spectinomycin as the antibiotic of choice for PPNG infections.
自1976年在加拿大首次分离出产青霉素酶淋病奈瑟菌（PPNG）以来，向渥太华疾病控制实验室中心报告的PPNG感染发病率稳步上升。截至1980年9月，共有66株PPNG菌株被送去进行生物学和遗传学特征分析以及每例病例流行病学方面的集中记录。超过90%的感染可明确追溯到在国外感染的患者或接触者；这表明加拿大目前尚无PPNG感染的流行中心。本报告包括这些菌株生物学特征的概要以及对初次抗生素治疗结果的分析，该分析说明了将壮观霉素视为PPNG感染首选抗生素的重要性。
