[不同性别和年龄大鼠在肌肉负荷和运动不足期间的血液及心脏胆碱酯酶活性]

[Blood and cardiac cholinesterase activity in rats of different sexes and ages during muscle loading and hypokinesia].

作者信息

Rozanova V D, Antonova G A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1978 Jul;64(7):999-1003.

Abstract

The activity of acetylcholinesterase (Ache) and butyrilcholinesterase (Bche) in the blood and the heart of 3 and 13-month old control male rats is considerably lower than in female rats. In old rats (25 months) no sex differences in the Ache and Bche were revealed in the heart. In 3 and 13-month old male and female rats, under conditions of muscular exercises, the Ache and Bche activity is lower, and in hypokinetic male rats--higher than that in respective control animals. In all the rats, irrespective of sex, age and motor conditions, the Ache and Bche activity tended to decrease, in direction from the sino-atrial node to the heart apex.

摘要

3个月和13个月大的雄性对照大鼠血液和心脏中的乙酰胆碱酯酶（Ache）和丁酰胆碱酯酶（Bche）活性明显低于雌性大鼠。在老年大鼠（25个月）中，心脏中未发现Ache和Bche的性别差异。在3个月和13个月大的雄性和雌性大鼠中，在肌肉运动条件下，Ache和Bche活性较低，而在运动不足的雄性大鼠中——高于相应的对照动物。在所有大鼠中，无论性别、年龄和运动状况如何，Ache和Bche活性均呈从窦房结向心尖方向降低的趋势。