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Studies of foetal death and foetal weight in guinea pigs fed polychlorinated biphenyls (PCB).

作者信息

Brunström B, Kihlström I, Lundkvist U

出版信息

Acta Pharmacol Toxicol (Copenh). 1982 Feb;50(2):100-3. doi: 10.1111/j.1600-0773.1982.tb00948.x.

DOI:10.1111/j.1600-0773.1982.tb00948.x
PMID:6803516
Abstract

Pregnant guinea pigs were fed a total dose of 100 mg of the commercial PCB preparation Clophen A50 during days 16 to 60 of gestation. This treatment caused severe foetal, but no maternal, death. Contrarily, a total dose of 25 mg or 100 mg of 2,2',4,4',5,5'-hexachlorobiphenyl (HCB) did not cause foetal death in the guinea pig. The prenatal growth rate was increased by a total dose of 25 mg, but not by 100 mg, of HCB.

摘要

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